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N6162

Sigma-Aldrich

Anti-Neuropeptide FF1 Receptor (NPFF1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-G protein-coupled Receptor 147 (GPR147), Anti-RFamide-related Peptide Receptor OT7T022

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~48 kDa

物種活性

human

技術

western blot: 1:500-1:1,000 using brain lysate

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... NPFFR1(64106)

一般說明

Neuropeptide FF receptor 1 (NPFF1) is a receptor for the protein RFamide-related peptide-3 (RFRP-3). It is expressed in the ovaries and the gene encoding it is localized on human chromosome 10q21.

免疫原

peptide corresponding to the C-terminal sequence (amino acids 418-430) and N-terminal sequence (amino acids 1-16) of the NPFF1 protein.

生化/生理作用

Neuropeptide FF receptor 1 (NPFF1) along with its ligand, prevents gonadotropin signaling.

外觀

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Identification and characterization of two G protein-coupled receptors for neuropeptide FF.
Bonini JA
The Journal of Biological Chemistry, 275(50), 39324-39331 (2000)
Hajime Oishi et al.
Endocrinology, 153(7), 3435-3445 (2012-06-14)
RFamide-related peptide-3 (RFRP-3), a mammalian ortholog of avian gonadotropin-inhibitory hormone, has pronounced inhibitory effects on reproduction in a number of species. RFRP-3 suppresses gonadotropin release at the hypothalamic and/or pituitary levels; however, increasing evidence also suggests putative functions within the

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