推薦產品
用途
sufficient for 100 colorimetric tests
檢測方法
colorimetric
相關疾病
cardiovascular diseases; cancer; hematological disorder
儲存溫度
−20°C
一般說明
醛脱氢酶（ALDH）是一类催化外源性醛和内源性醛的代谢、防止潜在反应性醛和毒性醛及其代谢物的积累的酶。除了它们在醛代谢中的作用外，ALDH酶还在其他细胞过程中起关键作用，例如细胞增殖，分化和存活。ALDH家族成员的突变与许多疾病有关，如心脏病、白内障和某些癌症。ALDH活性也可以作为某些干细胞群（包括造血干细胞和某些癌症干细胞）的标志物。
應用
醛脱氢酶活性比色检测试剂盒用于检测醛脱氢酶的活性。
特點和優勢
与高通量处理系统相容。
適合性
适用于对包括组织和细胞在内的多种样品中的醛脱氢酶（ALDH）进行测定
原則
醛脱氢酶活性比色检测试剂盒提供了一种可简单直接地检测各种样品中NAD依赖性ALDH活性的方法。ALDH活性通过酶偶联法检测，其中乙醛被ALDH氧化生成NADH，NADH与探针反应，产生比色(450 nm)产物，该产物与存在的ALDH活性成比例。一单位ALDH是指该酶在室温、pH 8.0条件下每分钟产生1.0 μmM NADH的量。
訊號詞
Danger
危險聲明
危險分類
Carc. 1B - Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
A Novel Long Non-Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis.
Yilu Qin et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 9(24), e2204046-e2204046 (2022-08-26)
Characterization of the CD49f+/CD44+/CD24- single-cell derived stem cell population in basal-like DCIS cells.
Duru N, et al.
Oncotarget, 7(30), 47511-47511 (2016)
Yilu Qin et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8(2), 2002232-2002232 (2021-01-30)
Cancer stem cells (CSCs) are considered the roots of cancer metastasis and recurrence (CSCs), due in part to their self-renewal and therapy resistance properties. However, the underlying mechanisms for the regulation of CSC stemness are poorly understood. Recently, increasing evidence
Ting Liu et al.
Bioengineered, 12(1), 7143-7155 (2021-09-22)
Cancer stem cell (CSC) has been confirmed to trigger tumor occurrence and progression and CSC can develop strategies to maintain a lower reactive oxygen species (ROS) level compared to cancer cells. However, the mechanisms contributing to ROS homeostasis in CSC
Xiaotian Xu et al.
Aging, 14(11), 4858-4873 (2022-06-10)
The roles of asparagine-linked glycosylation (ALG) members in tumorigenic process have been widely explored. However, their effects in colorectal cancer progression are still confusing. Here, we screened 12 ALGs' expression through online datasets and found that ALG10 was mostly upregulated
文章
AldeRed™ 588-A detects ALDH activity in cancer stem cells, aiding in cancer research.
AldeRed™ 588-A 可檢測癌症幹細胞中的 ALDH 活性，有助於癌症研究。
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務