生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
分子量
antigen 65 kDa
物種活性
human, mouse
濃度
~1 mg/mL
技術
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1:2,000
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... MMP24(10893)
mouse ... Mmp24(17391)
相關類別
一般說明
Matrix metalloproteinase-24 (MMP-24) is expressed majorly in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.
特異性
Reacts with reduced and native MMP-24. Recognizes the pro-form of MMP-24 as well as activation/breakdown products.
免疫原
synthetic peptide corresponding to the hinge region of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5).
生化／生理作用
Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.
外觀
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Sol de la Peña et al.
Disease markers, 2014, 285906-285906 (2014-03-29)
During progression of gastric cancer (GC), degradation of the extracellular matrix is mediated by the matrix metalloproteases (MMPs) and their tissue inhibitors (TIMPs): changes in the expression of these have been related to unfavorable prognosis in GC. To analyze the
A M Romanic et al.
American journal of physiology. Renal physiology, 281(2), F309-F317 (2001-07-18)
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade the extracellular matrix (ECM). The membrane-type matrix metalloproteinases (MT-MMPs) are a new family of MMPs that differ from other MMPs in that they have a transmembrane domain that anchors
Heather H Ross et al.
FEBS letters, 581(30), 5923-5928 (2007-12-08)
Membrane-type 5 matrix metalloproteinase (MT5-MMP) expression is ubiquitous in brain development while restricted to regions of neuroplasticity in adult. In the multipotent NT2 model of neurogenesis and differentiation, MT5-MMP is differentially expressed with significantly higher mRNA levels in the differentiated
E Llano et al.
Cancer research, 59(11), 2570-2576 (1999-06-11)
A cDNA encoding a new member of the membrane-type (MT) matrix metalloproteinase (MMP) family has been identified and cloned from a human brain cDNA library. The isolated cDNA encodes a polypeptide of 645 amino acids that displays a similar domain
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