M5404

Morantel citrate salt

• 同義詞: 1,4,5,6-Tetrahydro-1-methyl-2-(2-[3-methyl-2-thienyl]ethenyl)pyrimidine
• 經驗公式（希爾表示法）: C₁₂H₁₆N₂S · C₆H₈O₇
• CAS號碼: 69525-81-1
• 分子量：: 412.46
• EC號碼: 274-028-9
• MDL號碼: MFCD00079447
• 分類程式碼代碼: 51101500
• PubChem物質ID: 329818012

屬性

• 顏色: yellow
• 溶解度: H₂O: 4.0 mL, clear, yellow-green (200 mg + 4.0 mL H2O)
• 抗生素活性譜: parasites
• 作用方式: enzyme | inhibits
• SMILES 字串: OC(=O)CC(O)(CC(O)=O)C(O)=O.CN1CCCN=C1\C=C\c2sccc2C
• InChI: 1S/C12H16N2S.C6H8O7/c1-10-6-9-15-11(10)4-5-12-13-7-3-8-14(12)2;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-6,9H,3,7-8H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b5-4+;
• InChI 密鑰: OLOCXIJVDIVAHH-FXRZFVDSSA-N

描述

應用

Morantel is a anthelmintic compound used to treat parasitic infections in livestock. It is also used to study allosteric potentiation of rat neuronal nicotinic acetylcholine receptors (nAChRs) and is used to study nematode nicotinic receptors.

生化／生理作用

Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase.

Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase. Morantel increases the macroscopic currents evoked by acetylcholine (ACh) from nAChRs expressed in Xenopus laevis oocytes up to 8 times.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 + H312 + H332
• 防範說明: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves