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Merck
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文件

M0880

Sigma-Aldrich

甲磺酸乙酯

liquid

同義詞:

Ethyl mesylate, 甲烷磺酸乙酯

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About This Item

線性公式:
CH3SO3CH2CH3
CAS號碼:
分子量::
124.16
Beilstein:
773969
EC號碼:
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.25

形狀

liquid

折射率

n20/D 1.418 (lit.)

bp

85-86 °C/10 mmHg (lit.)

密度

1.206 g/mL at 20 °C

SMILES 字串

CCOS(C)(=O)=O

InChI

1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3

InChI 密鑰

PLUBXMRUUVWRLT-UHFFFAOYSA-N

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應用

甲磺酸乙酯已用于诱导小鼠胚胎成纤维细胞、酵母人胚肾细胞系和人淋巴细胞中的突变。

生化/生理作用

甲磺酸乙酯是一种DNA乙基化剂,对植物和动物具有致突变性,并在哺乳动物中具有致癌性。它已被用作DNA修复过程研究中的一种模范的烷化剂。EMS可诱导鸟嘌呤-胞嘧啶(G/C)碱基被取代为腺嘌呤-胸腺嘧啶(A/T)。EMS还可在基因组中产生点突变和单核苷酸多态性。MES是一种潜在的化学致突变剂,用于在水稻、小麦和拟南芥中诱导突变。

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

212.0 °F

閃點(°C)

100 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


分析證明 (COA)

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