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Merck
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文件

K4144

Sigma-Aldrich

KB-R7943

≥98% (HPLC), powder

同義詞:

2- [4-[(4-硝基苯基)甲氧基]苯基]乙酯,甲磺酸酯(1:1), 氨基甲硫基酸

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About This Item

經驗公式(希爾表示法):
C16H17N3O3S·CH3SO3H
CAS號碼:
分子量::
427.50
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

off-white to tan

溶解度

DMSO: >10 mg/mL

儲存溫度

2-8°C

SMILES 字串

CS(O)(=O)=O.NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1

InChI

1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)

InChI 密鑰

WGIKEBHIKKWJLG-UHFFFAOYSA-N

生化/生理作用

KB-R7943 抑制反转的 Na(+)/Ca(2+)交换剂 NCX。在心肌细胞中,Ca2+ 在收缩过程中从胞内存储中释放出来,在舒张过程中再被吸收回胞内。NCX 是防止 Ca2+ 超载的主要机制,因为钙离子跨质膜流入。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Mitochondrial dysfunction is a component of many neurodegenerative conditions. Measurement of oxygen consumption from intact neurons enables evaluation of mitochondrial bioenergetics under conditions that are more physiologically realistic compared to isolated mitochondria. However, mechanistic analysis of mitochondrial function in cells
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