生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen ~150 kDa
物種活性
human
包裝
antibody small pack of 25 μL
濃度
~1.0 mg/mL
技術
immunoprecipitation (IP): 2-5 μg using lysate of Raji cells
indirect immunofluorescence: 2-5 μg/mL using human HeLa cells
western blot: 1-2 μg/mL using whole extract of human HeLa cells
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... KTN1(3895)
一般說明
Kinectin (KTN1) protein is mainly located in the endoplasmic (ER) reticulum and is a large integral protein. This protein is made up of an N-terminal transmembrane domain and a C-terminal kinesin-binding domain. The KTN1 gene is mapped on the human chromosome at 14q22.3.
特異性
Anti-KTN1 recognizes human KTN1.
應用
Anti-KTN1 antibody produced in rabbit may be used in:
- immunoblotting
- immunoprecipitation
- immunofluorescence
生化/生理作用
Kinectin (KTN1) protein coheres to kinesin and is involved in vesicle transport on microtubules. This protein is also related to fibronectin-integrin adhesion sites.
外觀
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
儲存和穩定性
Store at at –20 °C. For continuous use, the product may be stored at 2–8 °C for up to one month. For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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The Journal of biological chemistry, 281(44), 33621-33634 (2006-09-05)
Kinectin is an integral membrane protein with many isoforms primarily found on the endoplasmic reticulum. It has been found to bind kinesin, Rho GTPase, and translation elongation factor-1delta. None of the existing models for the quaternary organization of the elongation
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