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Merck
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I7892

Sigma-Aldrich

Anti-Interferon-γ Inducible Protein antibody produced in goat

IgG fraction of antiserum, lyophilized powder

同義詞:

Anti-IP-10

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About This Item

Beilstein:
4294860
MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.41

生物源

goat

品質等級

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

human

技術

indirect ELISA: suitable
western blot: suitable

UniProt登錄號

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CXCL10(3627)

一般說明

Interferon-γ Inducible Protein (IP-10), also known as CXCL-10, is a cytokine that belongs to the CXC chemokine family. It is secreted in response to interferon-γ by neutrophils, monocytes, basophils, epithelial cells and keratinocytes. IP-10 is involved in chemotaxis, apoptosis, angiostasis and inhibits cell growth. The effects of IP-10 are mediated by its receptor, CXCR3. The major signalling pathways that are activated by IP-10 are those of MAPK, PKA, JNK, NF-κB and PI3K/Akt. Alteration of IP-10 levels has been observed in various infectious diseases caused bacteria, fungi and viruses such as dengue, Ebola and hepatitis B
Anti-Interferon-γ Inducible Protein antibody detects human IP-10.

免疫原

recombinant human IP-10.

應用

Anti-Interferon-γ Inducible Protein antibody may be used for immunoblotting at a working antibody concentration of 1-2 μg/ml. For ELISA, antibody concentration of 0.5-1.0 μg/ml is recommended.

外觀

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose

準備報告

Purified using protein G.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Morten Ruhwald et al.
Expert review of molecular diagnostics, 12(2), 175-187 (2012-03-01)
The current state-of-the-art tests for infection with Mycobacterium tuberculosis - the IFN-γ release assays - rely on accurate measurement of the cytokine IFN-γ. Many other potential biomarkers are expressed in concert with IFN-γ, and IP-10 in particular has shown promising
Mig and IP-10: CXC chemokines that target lymphocytes
Farber JM
Journal of Lipid Research, 61, 246-257 (1997)
Mingli Liu et al.
Cytokine & growth factor reviews, 22(3), 121-130 (2011-08-02)
C-X-C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family. CXCL10 binds CXCR3 receptor to induce chemotaxis, apoptosis, cell growth and angiostasis. Alterations

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