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Merck
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重要文件

I1279

Sigma-Aldrich

Isovelleral

solid

同義詞:

(+)-Isovelleral

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About This Item

經驗公式(希爾表示法):
C15H20O2
CAS號碼:
分子量::
232.32
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

形狀

solid

顏色

white

溶解度

H2O: insoluble
organic solvents: soluble

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(=O)C1=C[C@]2([H])CC(C)(C)C[C@]2([H])[C@]3(C)C[C@@]13C([H])=O

InChI

1S/C15H20O2/c1-13(2)5-10-4-11(7-16)15(9-17)8-14(15,3)12(10)6-13/h4,7,9-10,12H,5-6,8H2,1-3H3/t10-,12+,14-,15-/m1/s1

InChI 密鑰

PJAAESPGJOSQGZ-DZGBDDFRSA-N

生化/生理作用

Vanilloid receptor agonist.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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A Forsby et al.
Neuroscience letters, 217(1), 50-54 (1996-10-11)
The pungent sesquiterpenoid unsaturated dialdehydes polygodial and isovelleral, have previously been shown to increase the intracellular free calcium concentration [Ca2+]i in human neuroblastoma SH-SY5Y cells, partly by a release from intracellular Ca2+ stores, whereas the non-pungent compound epipolygodial, had no
M Jonassohn et al.
Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 49(7), 530-535 (1995-07-01)
The autoxidation of the two mutagenic and antimicrobial sesquiterpenes merulidial (1a) and isovelleral (5) generates a number of bioactive products that are suggested to be partly responsible for the mutagenic and antimicrobial activities of the two compounds. The biological activities
R P Bell et al.
The Journal of organic chemistry, 66(7), 2350-2357 (2001-04-03)
A general and efficient route to the marasmane skeleton is described. Total syntheses of two simple marasmanes (35 and 37) in racemic form were achieved using a MgI2-catalyzed rearrangement-cyclopropanation reaction of trimethylsilyl enol ether 31 derived from naphthalenone 30. The
D Smart et al.
European journal of pharmacology, 417(1-2), 51-58 (2001-04-13)
A full pharmacological characterisation of the recently cloned human vanilloid VR1 receptor was undertaken. In whole-cell patch clamp studies, capsaicin (10 microM) elicited a slowly activating/deactivating inward current in human embryonic kidney (HEK293) cells stably expressing human vanilloid VR1 receptor
Isabelle Aujard et al.
Bioorganic & medicinal chemistry, 13(22), 6145-6150 (2005-08-02)
The synthesis and in vitro cytotoxicity toward various tumor cell lines of (+/-)-tridemethylisovelleral, an analogue of the bioactive fungal sesquiterpene (+)-isovelleral retaining the bicyclo[4,1,0]hept-2-en-1,2-dicarbaldehyde system but lacking the three methyl groups, is reported. The cytotoxicity of tridemethylisovelleral toward several tumor

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