推薦產品
生物源
human
品質等級
重組細胞
expressed in HEK 293 cells
化驗
≥95% (SDS-PAGE)
形狀
lyophilized powder
效力
≤0.12 ng/mL EC50
品質
endotoxin tested
分子量
dimer 16 kDa (glycosylated)
包裝
poly bottle of 10 μg (in poly bottle)
製造商／商標名
HumanZyme
技術
cell culture | mammalian: suitable
雜質
≤1EU/mg
UniProt登錄號
儲存溫度
−20°C
基因資訊
human ... IFNA2(3440)
一般說明
The interferon α 2 (IFN-α2) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five α helices. IFN-α2B is found structurally stable at pH 7. The recombinant IFN-α is nonglycosylated compared to the natural human IFN-α.
生化／生理作用
Interferon α 2B (IFN-α 2B) belongs to the type I interferon protein family. It is produced by many cell types in response to viral infection. IFN-α 2B has antiproliferative and antitumor activities, as well as induction of apoptosis and the inflammatory response. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides and activates cytotoxic T-cells.
外觀
Lyophilized from a 0.2 μm filtered solution of 1x PBS.
準備報告
HumanKine IFN-α 2B is a glycosylated monomer expressed in HEK 293 cells with an apparent molecular mass of 16 kDa. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
分析報告
The specific activity was determined by the dose-dependent proliferation of WISH (heteroploid human amnion cell line) in presence of VSV ( vesicular stomatitis virus).
法律資訊
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Yining Wang et al.
Scientific reports, 11(1), 23465-23465 (2021-12-08)
Human coronavirus NL63 (HCoV-NL63) mainly affects young children and immunocompromised patients, causing morbidity and mortality in a subset of patients. Since no specific treatment is available, this study aims to explore the anti-SARS-CoV-2 agents including favipiravir and remdesivir for treating
Pengfei Li et al.
Science advances, 8(3), eabj5908-eabj5908 (2022-01-20)
Hepatotropic viruses naturally have narrow host and tissue tropisms, challenging the development of robust experimental models. The advent of organoid technology provides a unique opportunity for moving the field forward. Here, we demonstrate that three-dimensional cultured organoids from fetal and
Yingxian Yin et al.
Journal of medical virology, 91(8), 1440-1447 (2019-03-23)
Plaque assay plays an irreplaceable role in a variety of virological studies, including determining titers of viruses. Our previous study showed that a simple and highly repeatable plaque assay could be used for enterovirus 71 (EV-A71). Now, we show that
Formulation and stability of cytokine therapeutics
Lipiainen T, et al.
Journal of Pharmaceutical Sciences, 104(2), 307-326 (2015)
Yang Li et al.
Antiviral research, 176, 104743-104743 (2020-02-15)
Enteric viruses including hepatitis E virus (HEV), human norovirus (HuNV), and rotavirus are causing global health issues. The host interferon (IFN) response constitutes the first-line defense against viral infections. Melanoma Differentiation-Associated protein 5 (MDA5) is an important cytoplasmic receptor sensing
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務