推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen ~60 kDa
物種活性
human, mouse
包裝
antibody small pack of 25 μL
濃度
~1.0 mL/mL
技術
immunoprecipitation (IP): 5-10 μg using lysates of HEK-293T cells expressing human HOXA3
indirect immunofluorescence: 2-5 μg/mL using paraformaldehyde fixed HEK-293T cells over expressing human HOXA3
western blot: 2-4 μg/mL using lysates of HEK-293T cells over expressing human HOXA3
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... HOXA3(3200)
mouse ... Hoxa3(15400)
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一般說明
Homeobox A3 (HOXA3) transcription factor/protein belongs to the HOX family. The HOXA3 gene is mapped on the human chromosome at 7p15.2.
特異性
Anti-HOXA3 specifically recognizes HOXA3.
應用
Anti-HOXA3 antibody produced in rabbit may be used in:
- proximity ligation assay
- immunoblotting
- immunoprecipitation
- immunofluorescence
生化／生理作用
Disruption of the homeobox A3 (HOXA3) gene results in embryonic lethality, which was rescued by placing HOXD3. HOXA3 gene expression is upregulated during neovascularization as a result of injury indicating that HOXA3 promotes angiogenesis. Mutations of the HOXA3 gene are associated with defects in thymus organogenesis and parathyroid development.
外觀
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
儲存和穩定性
Store at −20 °C. For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze at −20 °C in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation. Discard working dilutions if not used within 12 hours.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
D Su et al.
Developmental biology, 236(2), 316-329 (2001-07-31)
The thymus and parathyroid glands in mice develop from a thymus/parathyroid primordium that forms from the endoderm of the third pharyngeal pouch. We investigated the molecular mechanisms that promote this unique process in which two distinct organs form from a
Maria Fernanda Setúbal Destro Rodrigues et al.
Genomics, 108(5-6), 185-193 (2016-11-09)
Approximately 300 homeobox loci were identified in the euchromatic regions of the human genome, of which 235 are probable functional genes and 65 are likely pseudogenes. Many of these genes play important roles in embryonic development and cell differentiation. Dysregulation
J M Greer et al.
Nature, 403(6770), 661-665 (2000-02-25)
Biological diversity is driven mainly by gene duplication followed by mutation and selection. This divergence in either regulatory or protein-coding sequences can result in quite different biological functions for even closely related genes. This concept is exemplified by the mammalian
Kimberly A Mace et al.
Journal of cell science, 118(Pt 12), 2567-2577 (2005-05-26)
Wound repair requires both the recruitment and coordination of numerous cell types including inflammatory cells, fibroblasts, endothelial and epithelial cells. Each cell type has a distinct set of cell behavior such as formation of granulation tissue and basement membrane, migration
Xiaolong Zheng et al.
iScience, 26(11), 108306-108306 (2023-11-29)
Human pluripotent stem cell (hPSC)-derived neurons have shown promise in treating spinal cord injury (SCI). We previously showed that hPSC-derived dorsal spinal γ-aminobutyric acid (GABA) neurons can alleviate spasticity and promote locomotion in rats with SCI, but their long-term safety
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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