生物源
chicken
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human
製造商／商標名
Genway 15-288-22299F
技術
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... M6PRBP1(10226)
一般說明
M6PRBP1 (Mannose-6-phosphate receptor binding protein 1) is a lipid droplet-associated protein, which is highly expressed, especially in adipocytes. It is also called perilipin 3 (PLIN3), and is a member of the PAT (perilipin, adipophilin, and the tail-interacting protein 47kDa) family of proteins, which includes five members. The N-terminal of this protein contains PAT-1 domain, and the C-terminal contains the PAT-2 domain. Both these domains are highly conserved regions.
免疫原
Immunogen Sequence: GI # 20127486, sequence 1-434
Recombinant mannose 6 phosphate receptor binding protein 1
應用
Anti-M6PRBP1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化／生理作用
Mannose-6-phosphate receptor binding protein 1 (M6PRBP1) has apolipoprotein-like properties and reorganizes liposomes into small lipid discs and plays a function in the biogenesis of cytosolic lipid droplets (LD). M6PRBP1 has a pivotal role in cytosolic lipid droplets (LD)-biogenesis in HL-60-derived neutrophils. It is associated with the synthesis and secretion of PGE2. M6PRBP1 also acts positively on HIV-1 and vaccinia virus production.
外觀
Solution in phosphate buffered saline containing 0.02% sodium azide.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Anna V Bulankina et al.
The Journal of cell biology, 185(4), 641-655 (2009-05-20)
TIP47 (tail-interacting protein of 47 kD) was characterized as a cargo selection device for mannose 6-phosphate receptors (MPRs), directing their transport from endosomes to the trans-Golgi network. In contrast, our current analysis shows that cytosolic TIP47 is not recruited to
Carole Bampi et al.
Virus research, 173(2), 354-363 (2013-01-26)
The cellular tail-interacting 47-kDa protein (TIP47) acts positively on HIV-1 and vaccinia virus production. We show here that TIP47, in contrast, acts as a restriction factor for Sendai virus production. This conclusion is supported by the occurrence of increased or
Jeffrey D Covington et al.
PloS one, 9(3), e91675-e91675 (2014-03-19)
Lipid droplet-associated proteins such as perilipin 3 (PLIN3) and coatomer GTPase proteins (GBF1, ARF1, Sec23a, and ARFRP1) are expressed in skeletal muscle but little is known so far as to their regulation of lipolysis. We aimed here to explore the
Fuyuki Nose et al.
PloS one, 8(8), e71542-e71542 (2013-08-13)
Cytosolic lipid droplets (LDs), which are now recognized as multifunctional organelles, accumulate in leukocytes under various inflammatory conditions. However, little is known about the characteristic features of LDs in neutrophils. In this study, we show that perilipin-3 (PLIN3; formerly called
Jeffrey D Covington et al.
European journal of endocrinology, 172(1), 47-58 (2014-10-25)
Polycystic ovary syndrome (PCOS) is associated with reduced adipose tissue lipolysis that can be rescued by aerobic exercise. We aimed to identify differences in the gene expression of perilipins and associated targets in adipose tissue in women with PCOS before
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