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GW10807F

Sigma-Aldrich

Anti-GAG polyprotein antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-GAG_HV1N5, Anti-Gag polyprotein

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

viral

製造商/商標名

Genway 15-288-10807F

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human immunodeficiency virus 1 ... Gag(155030)

免疫原

Immunogen Sequence: GI # 12831136, sequence 2-132
Recombinant gag polyprotein (HIV-1 vector pNL4-3)

應用

Anti-GAG polyprotein antibody produced in chicken is suitable for western blot analysis.

生化/生理作用

GAG is highly involved in RNA trafficking. It helps in transport of human immunodeficiency virus type 1 (HIV-1) RNA via diffusion within the cytoplasm. Ubiquitination of Gag enhances possibilities of its optimal function in virus release and maturation. It also recruits Ub ligases at the viral assembly site.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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Jianbo Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(48), E5205-E5213 (2014-11-19)
Full-length HIV-1 RNA plays a central role in viral replication by serving as the mRNA for essential viral proteins and as the genome packaged into infectious virions. Proper RNA trafficking is required for the functions of RNA and its encoded
U Schubert et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(24), 13057-13062 (2000-11-23)
Retrovirus assembly and maturation involve folding and transport of viral proteins to the virus assembly site followed by subsequent proteolytic cleavage of the Gag polyprotein within the nascent virion. We report that inhibiting proteasomes severely decreases the budding, maturation, and

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