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GE17-5317-10

Capto MMC

Cytiva 17-5317-10, pack of 25 mL

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About This Item

分類程式碼代碼:
23151817
NACRES:
NA.56

描述

Ion Exchanger Type (value)

包裝

pack of 25 mL

製造商/商標名

Cytiva 17-5317-10

基質

highly cross-linked agarose

樣品平均尺寸

75 μm (d50v)

cleaning in place

2-14

工作範圍

2-12

容量

>45 mg binding capacity (BSA/ml medium at 30 mS/cm)

適合性

suitable for bioprocess medium

一般說明

Capto MMC is a multimodal cation exchanger with a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges.
Dynamic binding capacity at 10% breakthrough as measured at a residence time of 2 min, 300 cm/h in a Tricorn 5/100 column with 10-cm bed height in 50 mM Sodium acetate, pH 4.75, 250 mM NaCl.

應用

Capto MMC is a multimodal cation exchanger, belonging to the Capto family of BioProcess media for fast, efficient and cost-effective Protein purification. Capto MMC combines Agarose base matrix developments with innovative ligand chemistry. It is composed of a rigid, high-fLow Agarose matrix and a novel multimodal ligand. The multimodal functionality gives Capto MMC a different selectivity, compared with traditional ion exchangers. It can be used to bind Proteins at the conductivity of the feed material and to solve specific purification challenges at both high and Low ionic strengths.

The ligand contains caroxylic group and thus its features partly resemble a weak cation exchanger, but for Capto MMC also several other types of interactions are involved, including hydrogen bonding and hydrophobic interactions.

Capto MMC is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Capto MMC meets industrial demands with security of supply and comprehensive technical and regulatory support.

特點和優勢

  • Multimodal cation exchanger with a novel selectivity.
  • High dynamic binding capacity at high conductivity increases productivity
  • High-volume throughput cuts process times
  • Smaller unit operations give cost-effective processing and reduce investments

儲存和穩定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

分析報告

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

法律資訊

Capto is a trademark of Cytiva

象形圖

Flame

訊號詞

Warning

危險聲明

儲存類別代碼

3 - Flammable liquids


分析證明 (COA)

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文章

Capto MMC is a multimodal cation exchanger with the properties of a weak cation exchanger. In addition to electrostatic interactions, the ligand structure provides for additional interaction modes such as hydrophobic interaction, hydrogen bonding, and thiophilic interaction.

Capto MMC 是一種多模式陽離子交換器,具有弱陽離子交換器的特性。除了靜電互動之外,配體結構還可提供其他互動模式,例如疏水互動、氫鍵和親硫互動。

This page describes the maintenance of media and storage conditions for multimodal chromatography using Cytiva products.

本頁說明使用 Cytiva 產品進行多模式層析時的培養基維護與儲存條件。

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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