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Merck
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重要文件

EMU147321

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Lgr4

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

CCTTTCTTTTATCCACCCAAAAGCCTTGTCTGGGTTGAAAGAACTCAAAGTCCTAACCCTCCAGAACAATCAGTTGAAAACAGTACCCAGTGAAGCCATTCGTGGACTGAGTGCTTTGCAGTCTCTACGCTTAGATGCCAACCATATTACCTCAGTCCCGGAGGACAGTTTTGAAGGGCTCGTTCAGTTGCGGCATCTGTGGCTGGATGACAACATCTTGACGGAAGTGCCTGTGCGTCCGCTCAGCAACCTGCCAACCCTGCAGGCGCTGACCTTGGCTCTCAACAACATCTCAAGCATCCCCGACTTCGCATTCACCAACCTTTCAAGCTTGGTAGTGCTGCATCTTCATAACAATAAAATTAAAAGCCTCAGTCAACACTGTT

Ensembl | 小鼠類登錄號

ENSMUSG00000050199

NCBI登錄號

NM_172671

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... LGR4(107515) , Lgr4(107515)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number

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Basit Salik et al.
Cancer cell, 38(2), 263-278 (2020-06-20)
Signals driving aberrant self-renewal in the heterogeneous leukemia stem cell (LSC) pool determine aggressiveness of acute myeloid leukemia (AML). We report that a positive modulator of canonical WNT signaling pathway, RSPO-LGR4, upregulates key self-renewal genes and is essential for LSC

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