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Key Documents

EMU076851

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Mfn2

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GGAATACGCCAGTGAGAAGCTACAGCTCATCATCAGTTACACCGGCTCTAACTGCAGCCACCAAGTCCAGCAGGAATTGTCTGGGACATTTGCTCATCTGTGCCAGCAAGTTGACATCACCCGAGATAATCTGGAGCAGGAAATTGCTGCCATGAACAAGAAAGTCGAGGCTCTGGATTCACTTCAGAGCAGAGCCAAACTGCTCAGGAATAAAGCTGGCTGGTTGGACAGCGAACTCAACATGTTCACACACCAGTACCTGCAGCCCAGCAGATAGTGGGCAGCCAGGGCGGACCTGCACGAAGAAGAGGCAGGGCCGACCTCCCATCAGCTCTAGTCCTTGGCCGCTGCAGAGAGAAGGAAAGCACCCAGTCTTGTACCAGTTACTCCCTACCCCCTGCAGGAAGACCCCTGGCTCATACCCTAATGGAGACCAACAAGGACTGGA

Ensembl | 小鼠類登錄號

ENSMUSG00000029020

NCBI登錄號

NP_573464

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... MFN2(170731) , Mfn2(170731)

相關類別

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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S Givvimani et al.
International journal of cardiology, 187, 325-333 (2015-04-05)
Mitochondria constitute 30% of cell volume and are engaged in two dynamic processes called fission and fusion, regulated by Drp-1 (dynamin related protein) and mitofusin 2 (Mfn2). Previously, we showed that Drp-1 inhibition attenuates cardiovascular dysfunction following pressure overload in
Alejandro Martorell-Riera et al.
The EMBO journal, 33(20), 2388-2407 (2014-08-26)
Mitochondrial fusion and fission is a dynamic process critical for the maintenance of mitochondrial function and cell viability. During excitotoxicity neuronal mitochondria are fragmented, but the mechanism underlying this process is poorly understood. Here, we show that Mfn2 is the

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