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Merck
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Key Documents

EMU065561

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Dynll1

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

CCTAGGAGCTCGCAGCAGCCGGCTGGCCTCTGCTCCACGGTAACCATGTGCGACCGGAAGGCGGTGATCAAAAATGCAGACATGTCGGAAGAGATGCAACAGGACTCGGTGGAGTGCGCTACCCAGGCGTTGGAGAAGTACAACATCGAGAAGGATATTGCGGCCCATATCAAGAAGGAGTTTGACAAGAAGTACAACCCTACCTGGCACTGCATTGTGGGCCGAAACTTCGGTAGTTATGTGGCACATGAAACCAAACACTTCATCTACTTCTACCTGGGTCAGGTGGCCATTCTTCTGTTCAAATCTGGTTAAAAGCATGGACTGTGCCAAACACCCAGTGATCCATCCAAAAACAAGGACTGCATCCAAATTCCAAATACCAGAGACTGAATCTTCAGCCTTGCTAAGGGA

Ensembl | 小鼠類登錄號

ENSMUSG00000009013

NCBI登錄號

NP_062656

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... DYNLL1(56455) , Dynll1(56455)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Yi-Ping Shih et al.
Biochimica et biophysica acta, 1853(12), 3258-3265 (2015-10-03)
DLC1 is a RhoGAP-containing tumor suppressor and many of DLC1's functions are absolutely dependent on its RhoGAP activity. Through its RhoGAP domain, DLC1 inhibits the activity of RhoA GTPase, which regulates actin cytoskeleton networks and dis/assembly of focal adhesions. Tensin1

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