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Merck
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重要文件

EMU012551

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Cftr

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GTCGTCTCGGCATTACAACCCTACATCTTCCTAGCAACGGTGCCAGGGCTAGTAGTCTTTATTTTACTGAGGGCCTACTTCCTTCATACAGCACAGCAGCTCAAACAACTGGAATCTGAAGGCAGGAGTCCAATTTTCACCCACCTTGTGACAAGCTTAAAAGGACTCTGGACACTTCGAGCCTTCCGACGCCAGACTTACTTTGAAACTCTGTTCCACAAAGCTCTGAATTTGCACACTGCCAACTGGTTTATGTATCTGGCAACCTTGCGCTGGTTCCAAATGAGAATAGACATGATATTTGTCCTCTTCTTCATTGTTGTTACCTTCATCTCCATTTTAACAACAGGTGAAGGAGAAGGAACAGCTGGTATTATTCTAACTTTAGCTATGAATATCATGAGTACTTTGCAGTGGGCTGTGA

Ensembl | 小鼠類登錄號

ENSMUSG00000041301

NCBI登錄號

NM_021050

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... CFTR(12638) , Cftr(12638)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number

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Ye Chun Ruan et al.
Journal of cell science, 127(Pt 20), 4396-4408 (2014-08-12)
Mutations in CFTR lead to dysfunction of tubular organs, which is currently attributed to impairment of its conductive properties. We now show that CFTR regulates tight junction assembly and epithelial cell differentiation through modulation of the ZO-1-ZONAB pathway. CFTR colocalizes

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