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Merck
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Key Documents

EHU160361

Sigma-Aldrich

MISSION® esiRNA

targeting human TIMM22

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

TGGAGGTTTTGCTGCTTTCTCTGCTGCGATTGATTATTACCTCCGGTGAGAGTAATTGCCTGCAGGGAAGGATGATGCCAGCCCCGGATCCGGGCTGCTCTCTGGAGGACAGTTTCTGTACCACACCAGGGCCTTGCTTCAGGGCCTGAAGACATTCATTTTCCCTCATGTCGTTGGTATTCTGAGGGAGCTGCCTGGCTTCTCTGCCTCCAGCCTTTGGGGTAGCCACACTTTGCTGCTCCTGGACTCCAGCCAGCCTTCACAGAGGACGTCCCGTGCCAGATTCTCTCACAGCAGATCGGGAGACAGGATGTTGACATATAGGAATTCAGCTCCACAAAGCTTCAGGCCTGACCACAGCTGGCCCTCTAGGTTGTTTGGTGTTGTGGGCACAGAGGTGACAGTGTCTCTGCAGGCACTCAGGAAGCTGTTCTACCTTGGAACTCCATGCAAC

Ensembl | 人類登錄號

ENSG00000177370

NCBI登錄號

NM_013337

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... TIMM22(29928) , TIMM22(29928)

相關類別

一般說明

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Sylvie Callegari et al.
FEBS letters, 590(23), 4147-4158 (2016-10-28)
Hydrophobic inner mitochondrial membrane proteins with internal targeting signals, such as the metabolite carriers, use the carrier translocase (TIM22 complex) for transport into the inner membrane. Defects in this transport pathway have been associated with neurodegenerative disorders. While the TIM22
Ridhima Gomkale et al.
Current biology : CB, 30(6), 1119-1127 (2020-03-07)
In mitochondria, the carrier translocase (TIM22 complex) facilitates membrane insertion of multi-spanning proteins with internal targeting signals into the inner membrane [1-3]. Tom70, a subunit of TOM complex, represents the major receptor for these precursors [2, 4-6]. After transport across

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