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Merck
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重要文件

EHU083491

Sigma-Aldrich

MISSION® esiRNA

targeting human LRSAM1

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

AACGCCTGGAGTACCAGATGTGTTTGGCAAAAGAAGCTGGGGCAGATGACATTCTCGACATCTCTAAATGTGAGCTCTCAGAGATTCCATTTGGAGCTTTTGCAACATGCAAAGTTCTGCAGAAGAAGGTGCTGATCGTCCACACGAATCACCTCACTTCCCTGCTTCCCAAATCCTGCAGCCTCCTGAGTCTGGCAACCATCAAGGTTCTAGATCTCCACGATAATCAGCTGACAGCCCTTCCTGACGATCTGGGGCAGCTGACTGCCCTCCAGGTCTTAAACGTGGAAAGGAATCAACTGATGCAGCTCCCACGTTCCATTGGGAACCTGACCCAGCTCCAGACTCTCAATGTTAAAGACAACAAGCTGAAGGAGCTTCCAGACACCGTGGGGGAGCTTCGAAGCCTGCGTACCCTCAACATCAGTGGAAACG

Ensembl | 人類登錄號

ENSG00000148356

NCBI登錄號

NM_138361

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... LRSAM1(90678) , LRSAM1(90678)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
KXU
OWU
LWS
QCS

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Ribhav Mishra et al.
The international journal of biochemistry & cell biology, 120, 105697-105697 (2020-01-27)
Accumulation of aberrant misfolded proteins is a major hallmark of several neurodegenerative diseases. Intracellular accumulations of such abnormal proteins are selectively cleared by the ubiquitin-proteasome system (UPS). But how the failure of misfolded protein degradation cause proteinopathies is still an
Anna Minaidou et al.
Cell journal, 20(3), 340-347 (2018-05-31)
Deleterious variants in LRSAM1, a RING finger ubiquitin ligase which is also known as TSG101-associated ligase (TAL), have recently been associated with Charcot-Marie-Tooth disease type 2P (CMT2P). The mechanism by which mutant LRSAM1 contributes to the development of neuropathy is

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