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Merck
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重要文件

EHU056781

Sigma-Aldrich

MISSION® esiRNA

targeting human ADAMTS3

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

TGAACCATGTTTGGGAGACAAGTCCATATTCTGTCAAATGGAAGTGTTGGCACGATACTGCTCCATACCAGGTTATAACAAGTTATGTTGTGAGTCCTGCAGCAAGCGCAGTAGCACCCTGCCACCACCATACCTTCTAGAAGCTGCTGAAACTCATGATGATGTCATCTCTAACCCTAGTGACCTCCCTAGATCTCTAGTGATGCCTACATCTTTGGTTCCTTATCATTCAGAGACCCCTGCAAAGAAGATGTCTTTGAGTAGCATCTCTTCAGTGGGAGGTCCAAATGCATATGCTGCTTTCAGGCCAAACAGTAAACCTGATGGTGCTAATTTACGCCAGAGGAGTGCTCAGCAAGCAGGAAGTAAGACTGTGAGACTGGTCACCGTACCATCCTCCCCACCCACCAAGAGGGTCCACCTCAGTTCAGCTTCACAAATGGCTG

Ensembl | 人類登錄號

ENSG00000156140

NCBI登錄號

NM_014243

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... ADAMTS3(9508) , ADAMTS3(9508)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Pingping Ren et al.
Scientific reports, 7(1), 12351-12351 (2017-09-29)
Sporadic aortic aneurysm and dissections (AADs) are common vascular diseases that carry a high mortality rate. ADAMTS-4 (a disintegrin-like and metalloproteinase with thrombospondin motifs-4) is a secreted proteinase involved in inflammation and matrix degradation. We previously showed ADAMTS-4 levels were
Zheng Li et al.
PloS one, 9(10), e109595-e109595 (2014-10-10)
The mechanistic basis of obesity-associated intervertebral disc degeneration (IDD) is unclear. Aberrant expression of aggrecan and its degrading enzymes ADAMTS-4 and ADAMTS-5 is implicated in the development of IDD. Here, we investigated the effect of leptin, a hormone with increased

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