D5321

D36 hydrate

≥98% (HPLC)

• 同義詞: 5-(2-methoxyphenyl)-1-(2-methylpropyl)-1H-Indole-3-acetamide Hydrate
• 經驗公式（希爾表示法）: C₂₁H₂₄N₂O₂ · xH₂O
• CAS號碼: 1228184-64-2
• 分子量：: 336.43 (anhydrous basis)
• MDL號碼: MFCD16875421
• 分類程式碼代碼: 51111800
• PubChem物質ID: 329798803

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to off-white
• 溶解度: DMSO: >10 mg/mL
• 起源: GlaxoSmithKline
• 儲存溫度: 2-8°C
• SMILES 字串: O.COc1ccccc1-c2ccc3n(CC(C)C)cc(CC(N)=O)c3c2
• InChI: 1S/C21H24N2O2.H2O/c1-14(2)12-23-13-16(11-21(22)24)18-10-15(8-9-19(18)23)17-6-4-5-7-20(17)25-3;/h4-10,13-14H,11-12H2,1-3H3,(H2,22,24);1H2
• InChI 密鑰: ZERKAKHVUQMJPW-UHFFFAOYSA-N

描述

生化／生理作用

D36 is an androgen receptor (AR) allosteric antagonist with inverse agonist properties. D36 inhibits both wild-type and agonist-induced AR activity and antagonized AR in a hormone-refractory model.

特點和優勢

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable