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D0758

Sigma-Aldrich

2′-Deoxyinosine 5′-triphosphate trisodium salt

synthetic, 95-97%

同義詞:

dITP-Na3

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About This Item

經驗公式(希爾表示法):
C10H12N4Na3O13P3
CAS號碼:
分子量::
558.11
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:

生物源

synthetic

化驗

95-97%

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[Na+].[Na+].[Na+].O[C@H]1C[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H15N4O13P3.3Na/c15-5-1-7(14-4-13-8-9(14)11-3-12-10(8)16)25-6(5)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;;/h3-7,15H,1-2H2,(H,20,21)(H,22,23)(H,11,12,16)(H2,17,18,19);;;/q;3*+1/p-3/t5-,6+,7+;;;/m0.../s1

InChI 密鑰

FHYSVBOUQFJKCI-PWDLANNDSA-K

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應用

2′-Deoxyinosine 5-triphosphate (dITP) may be formed by nitrosative deamination processes such as those that deaminate adenosine in DNA and RNA. dITP may be useful in studies of this process.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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T Auer et al.
Nucleic acids research, 24(24), 5021-5025 (1996-12-15)
The ability to selectively amplify RNA in the presence of genomic DNA of analogous sequence is cumbersome and requires implementation of critical controls for genes lacking introns. The convenient approaches of either designing oligonucleotide primers at the splice junction or
Gel compressions and artifact banding can be resolved in the same DNA sequence reaction.
K W McCrea et al.
BioTechniques, 15(5), 843-844 (1993-11-01)
ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.
Sakumi K, Abolhassani N, et al.
Mutation Research, 703, 4-50 (2010)
Anatoli Tchigvintsev et al.
The Biochemical journal, 437(2), 243-253 (2011-05-10)
Genomes of all free-living organisms encode the enzyme dUTPase (dUTP pyrophosphatase), which plays a key role in preventing uracil incorporation into DNA. In the present paper, we describe the biochemical and structural characterization of DUT1 (Saccharomyces cerevisiae dUTPase). The hydrolysis
Yoshihito Ueno et al.
Bioorganic & medicinal chemistry, 12(24), 6581-6586 (2004-11-24)
In this paper, we describe the synthesis and thermal stabilities of the triplexes containing either 2'-deoxyinosine (1) or 2'-deoxyxanthosine (3) in their second strands. It was found that the triplexes with the 2'-deoxy-5-methylcytidine(dM)*1:dC and dM*1:dA base triplets are thermally stable

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