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Merck
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重要文件

D003

Sigma-Aldrich

R(−)-Apocodeine hydrochloride

solid

同義詞:

R(−)-10-Methoxy-11-hydroxyaporphine hydrochloride

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About This Item

經驗公式(希爾表示法):
C18H19NO2 · HCl
CAS號碼:
分子量::
317.81
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

形狀

solid

光學活性

[α]22/D −43° in methanol(lit.)

顏色

off-white

溶解度

H2O: soluble

儲存溫度

2-8°C

SMILES 字串

Cl[H].[H][C@]12Cc3ccc(OC)c(O)c3-c4cccc(CCN1C)c24

生化/生理作用

Dopamine receptor agonist; apomorphine metabolite.

注意

Photosensitive

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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R V Smith et al.
Journal of natural products, 46(1), 79-91 (1983-01-01)
A solid basis for the M4-approach has been developed over the past 10 years. Recent examples of the production of difficult-to-synthesize mammalian metabolites through microbial transformations attest to the utility of the methodology. There is, however, much more to be
R van der Geest et al.
Journal of chromatography. B, Biomedical sciences and applications, 702(1-2), 131-141 (1998-02-04)
Analytical methods are described for the selective, rapid and sensitive determination of R- and S-apomorphine, apocodeine and isoapocodeine and the glucuronic acid and sulfate conjugates in plasma and urine. The methods involve liquid-liquid extraction followed by high-performance liquid chromatography with
Gessa, et al., eds.
Apomorphine and Other Dopaminomimetics, Vols. 1 and 2 (1981)
K Ishige et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(16), 6069-6076 (2001-08-07)
Oxidative stress is thought to be the cause of nerve cell death in many CNS pathologies, including ischemia, trauma, and neurodegenerative disease. Glutamate kills nerve cells that lack ionotropic glutamate receptors via the inhibition of the cystine-glutamate antiporter x(c)(-), resulting
Frédéric Libert et al.
Journal of mass spectrometry : JMS, 40(12), 1521-1525 (2005-11-15)
A method was developed and validated for the analysis of R(-)-apomorphine, (R-)-apocodeine and R(-)-norapomorphine in human plasma and urine with N-propylnorapomorphine as internal standard using gas chromatography/mass spectrometry (GC/MS) and single-ion monitoring after a single liquid-liquid extraction and silylation of

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