形狀
solid
光學活性
[α]22/D −43° in methanol(lit.)
顏色
off-white
溶解度
H2O: soluble
儲存溫度
2-8°C
SMILES 字串
Cl[H].[H][C@]12Cc3ccc(OC)c(O)c3-c4cccc(CCN1C)c24
基因資訊
human ... DRD1(1812) , DRD2(1813) , DRD3(1814) , DRD4(1815) , DRD5(1816)
生化/生理作用
Dopamine receptor agonist; apomorphine metabolite.
注意
Photosensitive
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
R V Smith et al.
Journal of natural products, 46(1), 79-91 (1983-01-01)
A solid basis for the M4-approach has been developed over the past 10 years. Recent examples of the production of difficult-to-synthesize mammalian metabolites through microbial transformations attest to the utility of the methodology. There is, however, much more to be
R van der Geest et al.
Journal of chromatography. B, Biomedical sciences and applications, 702(1-2), 131-141 (1998-02-04)
Analytical methods are described for the selective, rapid and sensitive determination of R- and S-apomorphine, apocodeine and isoapocodeine and the glucuronic acid and sulfate conjugates in plasma and urine. The methods involve liquid-liquid extraction followed by high-performance liquid chromatography with
Gessa, et al., eds.
Apomorphine and Other Dopaminomimetics, Vols. 1 and 2 (1981)
K Ishige et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(16), 6069-6076 (2001-08-07)
Oxidative stress is thought to be the cause of nerve cell death in many CNS pathologies, including ischemia, trauma, and neurodegenerative disease. Glutamate kills nerve cells that lack ionotropic glutamate receptors via the inhibition of the cystine-glutamate antiporter x(c)(-), resulting
Frédéric Libert et al.
Journal of mass spectrometry : JMS, 40(12), 1521-1525 (2005-11-15)
A method was developed and validated for the analysis of R(-)-apomorphine, (R-)-apocodeine and R(-)-norapomorphine in human plasma and urine with N-propylnorapomorphine as internal standard using gas chromatography/mass spectrometry (GC/MS) and single-ion monitoring after a single liquid-liquid extraction and silylation of
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