化驗
≥98% (HPLC)
形狀
powder
顏色
yellow
溶解度
DMSO: >10 mg/mL
H2O: insoluble 2 mg/mL (Lower concentrations not tested)
儲存溫度
2-8°C
SMILES 字串
NC(=O)c1sc2c(cc(cc2[n+]1[O-])C(F)(F)F)[N+]([O-])=O
生化/生理作用
Cyclapolin 9 is a Polo-like kinase (Plk) inhibitor. IC50 is 500 nM; selective against a panel of 20 kinases
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Nature chemical biology, 2(11), 608-617 (2006-10-10)
Polo-like kinases (Plks) have several functions in mitotic progression and are upregulated in many tumor types. Small-molecule Plk inhibitors would be valuable as tools for studying Plk biology and for developing antitumor agents. Guided by homology modeling of the Plk1
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