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About This Item
經驗公式（希爾表示法）:
C6H9NO6
CAS號碼:
分子量：:
191.14
Beilstein:
2417114
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
儲存溫度
−20°C
SMILES 字串
N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O
InChI
1S/C6H9NO6/c7-3(6(12)13)1-2(4(8)9)5(10)11/h2-3H,1,7H2,(H,8,9)(H,10,11)(H,12,13)/t3-/m0/s1
InChI 密鑰
UHBYWPGGCSDKFX-VKHMYHEASA-N
基因資訊
rat ... Grm2(24415)
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生化／生理作用
Gamma-carboxy-L-glutamic acid (GLA) is used as a metabotropic glutamate receptor (mGluR) subtype ligand wherein GLA is a group-II mGlu2 receptor and group-III mGlu7, mGlu8 antagonist and group-III mGlu4, mGlu6 agonist.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Randal X Moldrich et al.
European journal of pharmacology, 476(1-2), 3-16 (2003-09-13)
Metabotropic glutamate (mGlu) receptors have multiple actions on neuronal excitability through G-protein-linked modifications of enzymes and ion channels. They act presynaptically to modify glutamatergic and gamma-aminobutyric acid (GABA)-ergic transmission and can contribute to long-term changes in synaptic function. The recent
I Brabet et al.
Neuropharmacology, 37(8), 1043-1051 (1998-12-02)
In a previous study we reported that the addition of a carboxylic group to the mGlu receptor agonist aminocyclopentane-1,3-dicarboxylate (ACPD) changes its properties from agonist to antagonist at both mGlu1 and mGlu2 receptors, and resulted in an increase in affinity
Hilde Lavreysen et al.
Current medicinal chemistry, 15(7), 671-684 (2008-03-14)
Metabotropic glutamate (mGlu) receptors have received much attention, driven by a strong belief in the potential of these modulatory glutamate receptors as drug targets. So far, major drug discovery programs have largely focused on group I (mGlu1 and 5) and
G Gerber et al.
Neuroscience, 100(2), 393-406 (2000-09-29)
The effects of group II and group III metabotropic glutamate receptor agonists on synaptic responses evoked by primary afferent stimulation in the dorsal horn, but mostly substantia gelatinosa, neurons were studied in the spinal cord slice preparation using conventional intracellular
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