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C3394

Sigma-Aldrich

虫草素

from Cordyceps militaris, ≥98% (HPLC), powder, adenosine analogue

同義詞:

3′-脱氧腺苷

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About This Item

經驗公式（希爾表示法）:
C10H13N5O3
CAS號碼:
73-03-0
分子量：:
251.24
Beilstein:
35194
EC號碼:
200-791-4
MDL號碼:
MFCD00037998
分類程式碼代碼:
12352200
PubChem物質ID:
24892611
NACRES:
NA.77

product name

虫草素, from Cordyceps militaris

生物源

Cordyceps militaris

品質等級

200

形狀

powder

抗生素活性譜

fungi

作用方式

DNA synthesis | interferes
enzyme | inhibits

儲存溫度

−20°C

SMILES 字串

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)C[C@H]3O

InChI

1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1

InChI 密鑰

OFEZSBMBBKLLBJ-BAJZRUMYSA-N

基因資訊

rat ... Adora1(29290)

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一般說明

化学结构：核苷

生化／生理作用

虫草素是一种腺苷类似物，易于转化为5′-三磷酸虫草素；可用于RNA的3′-端标记。

特點和優勢

该化合物是受体分类及信号转导手册上腺苷酸环化酶页面上的特色化合物。想要浏览手册的其他页面， 请单击此处。
该化合物是环核苷酸和基因调控研究的特色产品。发现更多环核苷酸和基因调控特色产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息，请访问 sigma.com/discover-bsm。

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301 + H311 + H331

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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E N Kodama et al.
Biochemical pharmacology, 59(3), 273-281 (1999-12-28)
The nucleoside analogue cordycepin (3'-deoxyadenosine, 3'-dA) is substantially more cytotoxic to terminal deoxynucleotidyl transferase positive (TdT+) leukemic cells than to TdT leukemic cells in vitro in the presence of an adenosine deaminase inhibitor, deoxycoformycin (dCF), and has been considered as
Yukako Chiba et al.
Plant & cell physiology, 54(2), 180-194 (2012-12-12)
Control of mRNA half-life is a powerful strategy to adjust individual mRNA levels to various stress conditions, because the mRNA degradation rate controls not only the steady-state mRNA level but also the transition speed of mRNA levels. Here, we analyzed
Ying-Yi Chen et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(8-9), 768-778 (2012-04-03)
Cancer metastasis is a primary cause of cancer death. Antrodia cinnamomea (A. cinnamomea), a medicinal mushroom in Taiwan, has been shown antioxidant and anticancer activities. In this study, we first observed that ethanol extract of fruiting bodies of A. cinnamomea
Guifen Wu et al.
Cell reports, 30(7), 2387-2401 (2020-02-23)
Degradation of transcripts in human nuclei is primarily facilitated by the RNA exosome. To obtain substrate specificity, the exosome is aided by adaptors; in the nucleoplasm, those adaptors are the nuclear exosome-targeting (NEXT) complex and the poly(A) (pA) exosome-targeting (PAXT) connection.
Suman K Vodnala et al.
Journal of medicinal chemistry, 56(24), 9861-9873 (2013-11-29)
Novel methods for treatment of African trypanosomiasis, caused by infection with Trypanosoma brucei are needed. Cordycepin (3'-deoxyadenosine, 1a) is a powerful trypanocidal compound in vitro but is ineffective in vivo because of rapid metabolic degradation by adenosine deaminase (ADA). We
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