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重要文件

B7059

Sigma-Aldrich

Monoclonal Anti-Breast Cancer Resistance Protein antibody produced in mouse

~250 μg/mL, clone BXP-21, tissue culture supernatant, aqueous solution

同義詞:

Anti-ABCG2, Anti-BCRP

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

tissue culture supernatant

抗體產品種類

primary antibodies

無性繁殖

BXP-21, monoclonal

形狀

aqueous solution

分子量

antigen ~70 kDa

物種活性

human

濃度

~250 μg/mL

技術

flow cytometry: suitable
immunocytochemistry: 1:20-1:50 using acetone-fixed cytospin preparations
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable using pretreated human tissue
immunohistochemistry (frozen sections): 1:20 using acetone-fixed frozen sections
western blot: suitable

同型

IgG2a

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... ABCG2(9429)

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特異性

Reacts with an internal epitope of BCRP. Does not cross-react with the human MDR1, MRP1, MRP2 gene products.

免疫原

fusion protein containing human BCRP (amino acids 271-396) and maltose-binding protein.

應用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

外觀

Supplied in serum-free medium containing 0.7% bovine serum albumin and 0.1% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Hong Qi et al.
Experimental eye research, 86(1), 34-40 (2007-11-06)
Nerve growth factor (NGF), a member of the neurotrophin family, has been identified as an essential growth factor supporting stem cell self-renewal outside the nervous system and was previously shown to stimulate corneal epithelial proliferation both in vivo and in
Cathrine Elisabeth Olsen et al.
Biochemical pharmacology, 144, 63-77 (2017-08-09)
Here we report on the induction of resistance to photodynamic therapy (PDT) in the ABCG2-high human breast cancer cell line MA11 after repetitive PDT, using either Pheophorbide A (PhA) or di-sulphonated meso-tetraphenylchlorin (TPCS2a) as photosensitizer. Resistance to PhA-PDT was associated

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