B6312

14-3-3 Beta histidine-tagged human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), buffered aqueous glycerol solution

• 同義詞: 14-3-3 β, 14-3-3 protein Beta, GW128, HS1, KCIP-1 protein 1054, YWHAB
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 重組細胞: expressed in E. coli
• 品質等級: 200
• 化驗: ≥90% (SDS-PAGE)
• 形狀: buffered aqueous glycerol solution
• UniProt登錄號: P31946
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 基因資訊: human ... YWHAB(7529)

描述

生化／生理作用

14-3-3 proteins are a multifunctional protein family comprising seven mammalian isoforms that interact with over two hundred different intracellular molecules including kinases, phosphatases, transcription factors, scaffold proteins, and DNA. 14-3-3 proteins are involved in a multitude of biological functions and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control. 14-3-3 β participates in various processes, among which is the positive regulation of cell cycle progression and tumorigenesis. Over-expression of 14-3-3 β in NIH-3T3 cells confers tumorigenicity in nude mice via activation of the mitogen-activated protein kinase (MAPK) cascade.

外觀

Supplied as a 0.2 μm filtered solution in 50 mM Tris, pH 7.6, 1 mM EDTA, 1 mM DTT and 20% glycerol (w/v).

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)