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Merck
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重要文件

B2432

Sigma-Aldrich

8-Bromoadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer

≥98% (HPLC), solid

同義詞:

Rp-8-Br-cAMPS

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About This Item

經驗公式(希爾表示法):
C10H10BrN5O5PSNa
分子量::
446.15
分類程式碼代碼:
41106305
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

solid

包裝

vial of 5 μmol

溶解度

water: soluble

儲存溫度

−20°C

生化/生理作用

Competitive inhibitor of cyclic AMP-dependent protein kinase A (PKA) type I and II. Membrane-permeable analog of the cAMP inhibitor Rp-cAMPS (Prod. No. A-165).

特點和優勢

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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The Journal of biological chemistry, 270(35), 20599-20607 (1995-09-01)
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The signaling mechanisms underlying cell differentiation have been extensively studied with the use of rat PC12 cells as a model system. Nerve growth factor (NGF) is a trophic factor inducing PC12 cell differentiation through the activation of the p35/cyclin-dependent kinase

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