B1936

Borrelidin

from Streptomyces sp., ≥95% (HPLC), lyophilized powder

• 同義詞: 2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecarboxylic acid, Borrelidine, Cyclopentanecarboxylic acid, NSC 216128, Treponemycin
• 經驗公式（希爾表示法）: C₂₈H₄₃NO₆
• CAS號碼: 7184-60-3
• 分子量：: 489.64
• MDL號碼: MFCD01740784
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24724413

屬性

• 生物源: Streptomyces sp.
• 化驗: ≥95% (HPLC)
• 形狀: lyophilized powder
• 溶解度: DMF: soluble; DMSO: soluble; ethanol: soluble; ethyl acetate: soluble; methanol: soluble
• 抗生素活性譜: viruses
• 作用方式: enzyme | inhibits
• 儲存溫度: 2-8°C
• SMILES 字串: [H][C@]1(CCC[C@H]1C(O)=O)[C@@H]2C\C=C\C=C(C#N)[C@H](O)[C@@H](C)C[C@H](C)C[C@H](C)C[C@H](C)[C@@H](O)CC(=O)O2
• InChI: 1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
• InChI 密鑰: OJCKRNPLOZHAOU-UGKRXNSESA-N

描述

一般說明

Chemical structure: macrolide

生化／生理作用

Borrelidin is a potent angiogenesis inhibitor that induces apoptosis in capillary tube-forming cells. Also displays antimalarial activity against drug-resistant Plasmodia. Antimicrobial and selective threonyl t-RNA synthetase inhibitor.

安全資訊

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)