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Key Documents

AV39769

Sigma-Aldrich

Anti-CREB3L1 (AB2) antibody produced in rabbit

IgG fraction of antiserum

同義詞:

Anti-cAMP responsive element binding protein 3-like 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

57 kDa

物種活性

rabbit, mouse, bovine, rat, guinea pig, human

濃度

0.5 mg - 1 mg/mL

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... CREB3L1(90993)

一般說明

CREB3L1 (OASIS) is a transcription factor that is involved in the regulation of endoplasmic reticulum (ER) stress. It activates extracellular matrix gene expression and may play a role in the development of pancreas. CREB3L1 modulates the expression of the vasopressin gene in the hypothalamus of rats. EWSR1-CREB3L1 fusion transcript has been implicated in small cell osteosarcoma.
Rabbit Anti-CREB3L1 antibody recognizes bovine, human, mouse, rat, and canine CREB3L1.

免疫原

Synthetic peptide directed towards the N terminal region of human CREB3L1

應用

Rabbit Anti-CREB3L1 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.

生化/生理作用

The CREB3L1 gene encodes a protein with a transmembrane domain that is a transcriptional activator of the CREB/ATF family.

序列

Synthetic peptide located within the following region: MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFTENMEDF

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Larisa V Debelenko et al.
Genes, chromosomes & cancer, 50(12), 1054-1062 (2011-10-12)
Cellular morphology of small cell osteosarcoma, an aggressive variant of osteosarcoma, is similar to Ewing sarcoma, but its molecular pathogenesis is largely unknown. We report the case of a 12-year-old girl with multifocal small cell osteosarcoma positive for the Ewing
Ravi N Vellanki et al.
Endocrinology, 151(9), 4146-4157 (2010-07-30)
Old astrocyte specifically induced substance (OASIS) has previously been shown to be a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation that is similar to ATF6. In this study we investigated the expression and activation
Yan Fan et al.
The Journal of biological chemistry, 291(43), 22819-22829 (2016-09-10)
HIV-1 Tat is a major culprit for HIV/neuroAIDS. One of the consistent hallmarks of HIV/neuroAIDS is reactive astrocytes or astrocytosis, characterized by increased cytoplasmic accumulation of the intermediate filament glial fibrillary acidic protein (GFAP). We have shown that that Tat
Mingkwan Greenwood et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(11), 3810-3820 (2014-03-14)
Arginine vasopressin (AVP) is a neurohypophysial hormone regulating hydromineral homeostasis. Here we show that the mRNA encoding cAMP responsive element-binding protein-3 like-1 (CREB3L1), a transcription factor of the CREB/activating transcription factor (ATF) family, increases in expression in parallel with AVP

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