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Merck
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重要文件

A9052

Sigma-Aldrich

Atrial Natriuretic Peptide chicken

≥95% (HPLC)

同義詞:

ANF 1-29

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About This Item

經驗公式(希爾表示法):
C124H211N47O40S5
CAS號碼:
分子量::
3160.62
MDL號碼:
分類程式碼代碼:
12352200

化驗

≥95% (HPLC)

UniProt登錄號

儲存溫度

−20°C

基因資訊

chicken ... LOC395765(395765)

Amino Acid Sequence

Met-Met-Arg-Asp-Ser-Gly-Cys-Phe-Gly-Arg-Arg-Ile-Asp-Arg-Ile-Gly-Ser-Leu-Ser-Gly-Met-Gly-Cys-Asn-Gly-Ser-Arg-Lys-Asn [Disulfide bridge: 7–23]

生化/生理作用

Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.

品質

Has diuretic-natriuretic and hypotensive activity similar to mammalian ANF.

準備報告

Originally isolated from atrium.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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A Miyata et al.
Biochemical and biophysical research communications, 155(3), 1330-1337 (1988-09-30)
Morphological and pharmacological observations have suggested that chicken atrial natriuretic peptide (ANP) is different from mammalian ANP. The present survey for the as yet unidentified ANP in chicken heart was performed by monitoring the relaxant effect on chick rectum. From

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