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Key Documents

A8676

Sigma-Aldrich

阿普洛尔 盐酸盐

≥98% (TLC), powder

同義詞:

1-(o-烯丙基苯氧基)-3-(异丙基氨基)-2-丙醇 盐酸盐

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About This Item

經驗公式(希爾表示法):
C15H23NO2 · HCl
CAS號碼:
分子量::
285.81
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

化驗

≥98% (TLC)

形狀

powder

顏色

off-white

溶解度

H2O: 50 mg/mL

SMILES 字串

Cl[H].CC(C)NCC(O)COc1ccccc1CC=C

InChI

1S/C15H23NO2.ClH/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3;/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;1H

InChI 密鑰

RRCPAXJDDNWJBI-UHFFFAOYSA-N

基因資訊

尋找類似的產品? 前往 產品比較指南

應用

Alprenolol is a nonselective β-blocker and a serotonin 5HT1A receptor antagonist.

生化/生理作用

β1- and β2-adrenoceptor antagonist.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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A J Surman et al.
Journal of cardiovascular pharmacology, 21(1), 35-39 (1993-01-01)
We studied the effects of alprenolol and bromoacetylalprenololmenthane (BAAM) on rat left atria. Alprenolol and BAAM at 10(-7), 3 x 10(-7), and 10(-6) M inhibited the cardiac stimulation response slightly, which is indicative of membrane-stabilizing activity independent of beta-adrenoceptor blockade.
Noel Dew et al.
Colloids and surfaces. B, Biointerfaces, 89, 53-60 (2011-10-01)
To fully utilize the extended contact time of gel formulations a novel formulation with drug containing catanionic aggregates offering prolonged drug release and skin penetration were investigated. This study aimed to further explore the drug release process from catanionic vesicles
Marjukka Ikonen et al.
Colloids and surfaces. B, Biointerfaces, 78(2), 275-282 (2010-04-20)
In this work, isothermal titration calorimetry (ITC) combined with zeta potential measurements was used to study the binding and partitioning of three beta-blockers, alprenolol, labetalol and propranolol, and the local anaesthetic tetracaine into liposomes. The thermodynamic parameters of enthalpy, entropy
Y Shirayama et al.
European journal of pharmacology, 331(2-3), 319-323 (1997-07-23)
Desipramine, imipramine, clomipramine, (-)-propranolol, (-)-alprenolol, (+/-)-pentazocine and risperidone caused a concentration-dependent inhibition of 6 nM [3H]DTG (1,3-di-o-tolylguanidine)-defined sigma (sigma) binding with Ki values of about 0.5-2.5 microM in well-washed homogenates obtained from rat cerebral cortex. The saturation studies revealed that
J Zhang et al.
Psychopharmacology, 132(3), 281-288 (1997-08-01)
The beta-adrenoceptor antagonist as well as serotonin 5-HT1 receptor antagonist, (-)alprenolol, was found to potentiate the disrupting effect of the noncompetitive NMDA receptor antagonist, dizocilpine, on prepulse inhibition (PPI) of the acoustic startle response (ASR) in the rat. The facilitating

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