A7980

AC-41848 水合物

≥98% (HPLC), solid

• 同義詞: 1-[(2,4-Dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-5H-imidazo[1,2-a]azepinium bromide hydrate
• 經驗公式（希爾表示法）: C₂₁H₂₁BrCl₂N₂ · xH₂O
• CAS號碼: 400856-69-1
• 分子量：: 452.21 (anhydrous basis)
• MDL號碼: MFCD08705316
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24724399
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 儲存條件: desiccated; under inert gas
• 溶解度: DMSO: ~14 mg/mL; H₂O: >5 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: [Br-].[H]O[H].Clc1ccc(C[n+]2cc(-c3ccccc3)n4CCCCCc24)c(Cl)c1
• InChI: 1S/C21H21Cl2N2.BrH.H2O/c22-18-11-10-17(19(23)13-18)14-24-15-20(16-7-3-1-4-8-16)25-12-6-2-5-9-21(24)25;;/h1,3-4,7-8,10-11,13,15H,2,5-6,9,12,14H2;1H;1H2/q+1;;/p-1
• InChI 密鑰: FPOBEBBUBSFIIA-UHFFFAOYSA-M

描述

應用

AC-41848 is a potent, cell permeable, and subtype selective retinoic acid receptor RARγ agonist.

生化／生理作用

AC-41848 is a potent, cell permeable, subtype selective retinoic acid receptor RARγ agonist. AC-41848 has high selectivity (92%) for RARγ. EC₅₀ = 5.9 μM.

特點和優勢

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves