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A4660

Sigma-Aldrich

6-硫代鸟嘌呤

Hybri-Max, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

同義詞:

2-氨基-6-巯嘌呤, 2-氨基-6巯基嘌呤

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About This Item

經驗公式(希爾表示法):
C5H5N5S
CAS號碼:
分子量::
167.19
Beilstein:
157765
EC號碼:
MDL號碼:
分類程式碼代碼:
12352207
PubChem物質ID:
NACRES:
NA.75

生物源

synthetic (organic)

品質等級

等級

Hybri-Max

無菌

γ-irradiated

產品線

BioXtra

化驗

~98%

形狀

lyophilized powder

濃度

50 ×

技術

cell culture | hybridoma: suitable

雜質

endotoxin, tested

mp

≥300 °C (lit.)

溶解度

1 M NaOH: 50 mg/mL, clear to slightly hazy

儲存溫度

room temp

SMILES 字串

NC1=Nc2nc[nH]c2C(=S)N1

InChI

1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

InChI 密鑰

WYWHKKSPHMUBEB-UHFFFAOYSA-N

基因資訊

尋找類似的產品? 前往 產品比較指南

應用

在杂交瘤形成应用中作为选择剂。

生化/生理作用

核糖基化并通过与天然嘌呤碱相同的途径磷酸化;作为核苷酸,抑制参与核酸合成的多种细胞过程。作为白血病的有效治疗方法已有悠久的历史。

重構

10mL 无菌细胞培养基可复原一小瓶本品。储存液足以制备 500mL 培养基。最终工作浓度:30μM 2-氨基-6-巯基嘌呤。

法律資訊

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Donghui Li et al.
Nucleic acids research, 49(5), 2642-2654 (2021-02-17)
The CRISPR/Cas9 system is a technology for genome engineering, which has been applied to indel mutations in genes as well as targeted gene deletion and replacement. Here, we describe paired gRNA deletions along the PIGA locus on the human X
Quentin Gueranger et al.
The Journal of investigative dermatology, 134(5), 1408-1417 (2013-11-29)
Damage to skin DNA by solar UV is largely unavoidable, and an optimal cellular response to it requires the coordinated operation of proteins in numerous pathways. A fully functional DNA repair proteome for removing harmful DNA lesions is a prerequisite
Mark Drost et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(23), 9403-9408 (2013-05-22)
In many individuals suspected of the common cancer predisposition Lynch syndrome, variants of unclear significance (VUS), rather than an obviously pathogenic mutations, are identified in one of the DNA mismatch repair (MMR) genes. The uncertainty of whether such VUS inactivate
N K H de Boer et al.
Digestion, 73(1), 25-31 (2006-02-24)
Recently, the suggestion to use 6-thioguanine (6-TG) as an alternative thiopurine in patients with inflammatory bowel disease (IBD) has been discarded due to reports about possible (hepato) toxicity. During meetings arranged in Vienna and Prague in 2004, European experts applying
Xingjie Ren et al.
Science advances, 7(38), eabi4360-eabi4360 (2021-09-16)
[Figure: see text].

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