全部照片(5)
About This Item
經驗公式（希爾表示法）:
C5H5N5 · HNO3
CAS號碼:
分子量：:
198.14
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51
推薦產品
生物源
synthetic
品質等級
化驗
≥99%
形狀
powder
溶解度
water: 50 mg/mL, clear, faintly to light yellow
SMILES 字串
O[N+]([O-])=O.Nc1ncc2[nH]cnc2n1
InChI
1S/C5H5N5.HNO3/c6-5-7-1-3-4(10-5)9-2-8-3;2-1(3)4/h1-2H,(H3,6,7,8,9,10);(H,2,3,4)
InChI 密鑰
PGDNOZBGABWZLD-UHFFFAOYSA-N
應用
2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR).
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Yasumi Endoh et al.
Journal of immunology (Baltimore, Md. : 1950), 182(4), 2258-2268 (2009-02-10)
The S100 calcium-binding proteins S100A8 and S100A9 are elevated systemically in patients with viral infections. The S100A8-S100A9 complex facilitated viral replication in human CD4(+) T lymphocytes latently infected with HIV-1- and S100A8-induced HIV-1 transcriptional activity. Mechanisms inducing the S100 genes
Michael E Lindquist et al.
Virology, 413(1), 103-110 (2011-03-08)
We performed experiments to determine the effect of PKR activation on respiratory syncytial virus (RSV) replication. We first determined that RSV infection activates PKR which induces the phosphorylation of eIF2α, resulting in the formation of host stress granules. We used
Chen-Hsuan Wang et al.
Brain research bulletin, 79(3-4), 169-176 (2009-05-12)
Molecules involved in self-protection of neurons against glucose/oxygen/serum deprivation (GOSD) were investigated. Trypan blue dye exclusion assay, Western blotting, ELISA, cytokine antibody array and chemical blocking assay were applied in the study. Results showed that early induction (at 6h of
Junpei Teramachi et al.
Experimental cell research, 316(19), 3254-3262 (2010-08-24)
Double-stranded RNA-dependent protein kinase (PKR) plays a critical role in antiviral defence of the host cells. PKR is also involved in cell cycle progression, cell proliferation, cell differentiation, tumorigenesis, and apoptosis. We previously reported that PKR is required for differentiation
Renata M S Pereira et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(2), 617-626 (2009-10-09)
The evolution of Leishmania infection depends on the balance between microbicidal and suppressor macrophage functions. Double-stranded RNA (dsRNA)-activated protein kinase R (PKR), a classic antiviral protein, is able to regulate a number of signaling pathways and macrophage functions. We investigated
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