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Merck
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重要文件

A0726

Sigma-Aldrich

Activin Receptor-Like Kinase 7/Fc Chimera from rat

>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

同義詞:

ALK-7

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About This Item

MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.32

生物源

rat

重組細胞

expressed in NSO cells

化驗

>90% (SDS-PAGE)

形狀

lyophilized powder

分子量

47-55 kDa by SDS-PAGE (reducing)
calculated mol wt ~35.7 kDa

包裝

pkg of 100 μg

儲存條件

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

技術

cell culture | mammalian: suitable

雜質

endotoxin, tested

UniProt登錄號

儲存溫度

−20°C

基因資訊

生化/生理作用

ALK-7 is a type I receptor of the serine/threonine kinases and is expressed in the adult central nervous system. Type I and II receptors bind ligands in the TGF-β superfamily.

外觀

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

分析報告

Can be used as a calibrator for ALK-7 antibodies.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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M Rydén et al.
The Journal of biological chemistry, 271(48), 30603-30609 (1996-11-29)
Receptor serine-threonine kinases (RSTK) mediate inhibitory as well as stimulatory signals for growth and differentiation by binding to members of the transforming growth factor-beta (TGF-beta) superfamily. Over 12 different RSTKs have been isolated so far, displaying wide expression in peripheral
P ten Dijke et al.
Oncogene, 8(10), 2879-2887 (1993-10-01)
Human cDNA clones encoding four novel putative transmembrane protein serine/threonine kinases, denoted activin receptor-like kinase (ALK) -1, -2, -3 and -4, were obtained using a polymerase chain reaction (PCR)-based strategy. The PCR primers were designed based upon the sequence similarity

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