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Merck
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文件

A0362

Sigma-Aldrich

Adjuplex佐剂 ™ 疫苗

Concentrate, sterile

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.25

無菌

sterile

品質

NOT FOR HUMAN USE

運輸包裝

wet ice

儲存溫度

2-8°C

一般說明

佐剂可增强对疫苗的免疫反应而无反应原性，并且已证明优于明矾、弗氏佐剂、Ribi-R730和许多其他实验佐剂。在实验动物中，已证明Adjuplex可改善对多种实验性人类疫苗（包括HIV，流感，轮状病毒和疟疾）的保护性免疫应答。

應用

佐剂适用于所有类型的抗原，例如整个生物体（存活或灭活）、蛋白质、多糖、DNA、病毒载体和VLP。它适用于所有给药途径，包括肌内、皮下、真皮内和粘膜（包括鼻内）。
佐剂 ™ 疫苗佐剂已被用于研究佐剂对 DNA 疫苗接种的影响。

其他說明

Adjuplex 疫苗佐剂是一种非变性佐剂，不含油、清洁剂、防腐剂或动物或细菌来源的成分。佐剂为非免疫原性，不含过敏原，酶，汞，铝和其他金属。

數量

1ml 的佐剂足以配制十支0.5ml的疫苗。

法律資訊

Adjuplex is a trademark of Advanced BioAdjuvants, LLC

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H319

危險分類

Eye Irrit. 2

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is used to solubilize Adjuplex ™ Vaccine Adjuvant reagent, Product A0362? 

    The Adjuplex™ Vaccine Adjuvant reagent (Product No. A0362) can be solubilized in a sterile diluent such as phosphate buffered saline (PBS).  Endotoxin-free Dulbecco’s PBS without Ca2+ and Mg2+ is recommended, while unbuffered normal saline is NOT recommended.

  6. What are the adjuvant components of the Adjuplex™ Vaccine Adjuvant reagent, Product A0362? 

    The formulation of Adjuplex™ Vaccine Adjuvant reagent (Product A0362) is proprietary.  The formulation does not contain any components of animal-origin, microbial origin, or from recombinant technology.

  7. What is the recommended volume dose used with Adjuplex™ Vaccine Adjuvant reagent, Product A0362? 

    In general, the dosage volume of Adjuplex™ Vaccine Adjuvant (Product A0362) combined with antigen should be comparable to the dosage volumes used for other adjuvants.  Typical volumes are 0.1-0.2 mL for mice, 0.5 mL for rats and guinea pigs, and 1 mL for rabbits and goats, but these volumes are guidelines only.   For best effect, a dose response curve should be prepared.  

  8. What methods of administration are recommended for antigen preparations using Adjuplex™ Vaccine Adjuvant reagent, Product A0362? 

    Adjuplex™ Vaccine Adjuvant (Product A0362) has been found to be suitable for all routes of administration, including intramuscular, subcutaneous, intradermal, and mucosal including intranasal.  

  9. What types of antigen may be used with Adjuplex™ Vaccine Adjuvant reagent, Product A0362? 

    Adjuplex™ Vaccine Adjuvant (Product A0362) is suitable for use with all types of antigens including whole organism (live or inactivated), protein, polysaccharide, DNA, virus vector, and VLP antigens.  

  10. Can prepared solutions of antigen and Adjuplex™ Vaccine Adjuvant reagent, Product A0362, be stored and reused?

    We do not recommend reusing diluted solutions of Adjuplex™ Vaccine Adjuvant reagent (Product A0362) due to risk of contamination.  We recommend preparing fresh dilutions of Adjuplex™ Vaccine Adjuvant reagent with antigen each time prior to use.

  11. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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