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About This Item
經驗公式（希爾表示法）:
C20H14N2O3 · HCl
CAS號碼:
分子量：:
366.80
Beilstein:
4631860
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.32
推薦產品
產品線
BioReagent
化驗
≥99.0% (UV)
形狀
crystals
mp
>300 °C (lit.)
溶解度
ethanol: soluble
methanol: soluble
螢光
λex 498 nm; λem 520 nm in methanol
適合性
suitable for fluorescence
SMILES 字串
Cl.Nc1ccc2c(OC3=CC(=N)C=CC3=C2c4ccccc4C(O)=O)c1
InChI
1S/C20H14N2O3.ClH/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24;/h1-10,21H,22H2,(H,23,24);1H
InChI 密鑰
JNGRENQDBKMCCR-UHFFFAOYSA-N
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相關類別
一般說明
罗丹明110或R110是一种三苯甲烷染料，可发射出强烈的绿色荧光。能发出高强度荧光是由于存在作为给电子基团的氨基。罗丹明110的最大激发光谱和发射光谱分别为502.4/521.6521.6 nm。
應用
罗丹明110被用于测定具有准确的动力学参数的蛋白酶活性。它被用于测量诱导细胞凋亡的半胱天冬酶活性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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Xian Zhang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(8), 1667-1672 (2003-05-09)
A simple and sensitive fluorescence quenching method for the determination of trace nitrite has been developed. The method is based on the reaction of Rhodamine 110 with nitrite in acidic medium to form a new compound, which has much lower
Aya Shibata et al.
Bioorganic & medicinal chemistry letters, 18(7), 2246-2249 (2008-03-25)
We have developed a new fluorescent probe for biological thiol. The probe was synthesized by the modification of the 2,4-dinitrobenzenesulfonyl group with rhodamine 110. The selective detection of thiol species such as cysteine or glutathione was achieved in biological conditions.
Saijie Zhu et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 37(5), 573-580 (2009-05-16)
The present study was aimed to investigate the effects of polyoxyethylene (40) stearate (PS), a non-ionic surfactant, on the activity of P-glycoprotein (P-gp) and six major cytochrome P450 (CYP) isoforms. An in vitro diffusion chamber system was utilized to estimate
H Hug et al.
Biochemistry, 38(42), 13906-13911 (1999-10-21)
Caspases (cysteine aspartate-specific proteases) are a structurally related group of cysteine proteases that cleave peptide bonds following specific recognition sequences. They play a central role in activating apoptosis of vertebrate cells. To measure apoptosis induced by various stimuli and at
Melissa M Yatzeck et al.
Bioorganic & medicinal chemistry letters, 18(22), 5864-5866 (2008-07-04)
A derivative of rhodamine 110 has been designed and assessed as a probe for cytochrome P450 activity. This probe is the first to utilize a 'trimethyl lock' that is triggered by cleavage of an ether bond. In vitro, fluorescence was
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