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81357

Sigma-Aldrich

多聚谷氨酸酪氨酸 钠盐

suitable for ligand binding assays, Mol wt 20,000-50,000

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.26

product name

多聚谷氨酸酪氨酸 钠盐, mol wt 20,000-50,000, Glu:Tyr 4:1

品質等級

形狀

powder

饋電比

Glu:Tyr (4:1)

分子量

20,000-50,000

技術

ligand binding assay: suitable

顏色

white to off-white

儲存溫度

−20°C

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生化/生理作用

Poly(Glu,Tyr) (poly(Glu,Tyr) 4:1 random copolymer) is used as a substrate for the evaluation of protein tyrosine kinase(s).
Poly(Glu,Tyr) 4:1 is a polyamino acid used in the manufacture of electrochemical biosensors for detection of reactions such as Fenton induced tyrosine oxidation.

其他說明

有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Morten R Clausen et al.
Journal of agricultural and food chemistry, 56(18), 8692-8698 (2008-09-02)
Oxidation of 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) by lactoperoxidase was found to be inhibited by tyrosine-containing random amino acid copolymers but not by tyrosine. Both electrostatic effects and polymer size were found to be important by comparison of negatively and positively charged copolymers
Masanobu Chiku et al.
Biosensors & bioelectronics, 26(1), 235-240 (2010-07-17)
In this report, we determined protein tyrosine kinase (PTKs) activity in human epidermoid carcinoma cells (A431) by employing a novel electrochemical method using boron-doped diamond (BDD) electrodes that enables the electrochemical oxidation of tyrosine (Tyr), phosphorylated Tyr (Tyr-P) and sulfated
J Shao et al.
Diabetes, 49(4), 603-610 (2000-06-28)
The cellular mechanisms for the insulin resistance of pregnancy and gestational diabetes mellitus (GDM) are unknown. The membrane protein plasma cell membrane glycoprotein-1 (PC-1) has been identified as an inhibitor of insulin receptor tyrosine kinase (IRTK) activity. We investigated insulin
Na Qu et al.
Biosensors & bioelectronics, 26(5), 2292-2296 (2010-11-03)
A simple and sensitive electrochemical biosensor was used to detect tyrosine oxidation induced by hydroxyl radicals generated by Fenton reaction (Fe(2+)/H(2)O(2)). Poly(glu, tyr) (4:1) peptides were immobilized on indium tin oxide (ITO) electrode surface via layer-by-layer assembly technique, and Os(bpy)(3)(2+)-mediated
Jane A Beebe et al.
The Journal of biological chemistry, 278(29), 26810-26816 (2003-05-15)
The expression of certain COOH-terminal truncation mutants of the epidermal growth factor receptor (EGFR) can lead to cell transformation, and with ligand stimulation, a broader spectrum of phosphorylated proteins appears compared with EGF-treated cells expressing wild-type EGFR. Accordingly, it has

文章

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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