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64951

Sigma-Aldrich

7-甲氧基香豆素

suitable for fluorescence, ≥98.0% (TLC)

同義詞:

Methyl umbelliferyl ether, 赫尼亚林

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About This Item

經驗公式(希爾表示法):
C10H8O3
CAS號碼:
分子量::
176.17
Beilstein:
141728
EC號碼:
MDL號碼:
分類程式碼代碼:
85151701
PubChem物質ID:
NACRES:
NA.32

化驗

≥98.0% (TLC)

形狀

solid

mp

117-121 °C (lit.)

溶解度

DMF: soluble
acetonitrile: soluble
alcohols: soluble
chloroform: soluble

螢光

λex 350 nm; λem 385 nm (Reaction product)
λex 350 nm; λem 385 nm in chloroform

適合性

suitable for fluorescence

SMILES 字串

COc1ccc2C=CC(=O)Oc2c1

InChI

1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3

InChI 密鑰

LIIALPBMIOVAHH-UHFFFAOYSA-N

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應用

7-Methoxycoumarin (Herniarin) is used to study antioxidant and hepatoprotective properties and its activity as an allergen. 7-Methoxycoumarin may be used as a reference material in the purification, separation and analysis of coumarin compounds.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Sandesh Sancheti et al.
Drug and chemical toxicology, 36(1), 42-47 (2012-11-07)
The available conventional remedies for the treatment of drug-induced liver diseases are highly inadequate and possess serious adverse effects; therefore, the development of new, effective drugs is considered necessary. This article explores the hepatoprotective and antioxidant potential of 7-methylcoumarin (MC)
W Legrum et al.
The Journal of pharmacology and experimental therapeutics, 221(3), 790-794 (1982-06-01)
Pretreatment of rats with cobaltous chloride has been shown previously to reduce the content of cytochrome P-450 in the hepatic microsomal protein. This is accompanied by a corresponding decrease in substrate oxidation, e.g. ethyl morphine demethylation, in vitro. The present
Jin-Fang Nie et al.
Talanta, 75(5), 1260-1269 (2008-07-01)
This paper reports a simple, rapid, and effective method for quantitative analysis of 6-methylcoumarin (6-MC) and 7-methoxycoumarin (7-MOC) in cosmetics using excitation-emission matrix (EEM) fluorescence coupled with second-order calibration. After simple pretreatments, the adopted calibration algorithms exploiting the second-order advantage
Adriana Eliasová et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 59(7-8), 543-548 (2005-04-09)
The responses of young plants of diploid and tetraploid Matricaria chamomilla cultivars to abiotic stress were studied. The course of quantitative changes of main leaf secondary metabolites was evaluated within an interval from 6 h before to 54 h after
P Paterson et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(11), 849-859 (1984-11-01)
Pretreatment of rats with phenobarbitone increased hepatic microsomal 7-methoxy-and 7-ethoxy-coumarin O-dealkylase activities. Pretreatment with beta-naphthoflavone increased only the 7-ethoxycoumarin O-dealkylase activity. The addition of metyrapone in vitro inhibited the O-dealkylations to different extents. Similar results were obtained with diphenyloxazole and

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