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Merck
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文件

61760

Sigma-Aldrich

Lectin from Canavalia ensiformis

lyophilized, ≥50% (GE), powder

同義詞:

刀豆素 A

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.56

生物源

Canavalia ensiformis

形狀

powder

品質

lyophilized

分子量

Mr ~53000

濃度

≥50% (GE)

技術

XRF: suitable

儲存溫度

2-8°C

生化/生理作用

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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H. Bittiger and H.P. Schnebli, eds.
Concanavalin A as a Tool, 639-639 (1976)
Lectins in the isolation of receptors on lymphocytes.
J J Marchalonis
Methods in enzymology, 150, 463-477 (1987-01-01)
Dongxu Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 144, 111576-111576 (2020-08-05)
Plant-derived dietary lectins have been reported to be involved in the pathogenesis of several inflammatory diseases, including hepatitis, inflammatory bowel disease, diabetes, and celiac disease. In this present study, we aimed to assess whether green tea polyphenols (GTPs) exerts protective

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