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281M-8

Sigma-Aldrich

MART-1 (Melan A) (A103) Mouse Monoclonal Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

A103, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (281M-84)
vial of 0.5 mL concentrate (281M-85)
bottle of 1.0 mL predilute (281M-87)
vial of 1.0 mL concentrate (281M-86)
bottle of 7.0 mL predilute (281M-88)

製造商／商標名

Cell Marque™

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同型

IgG1

控制

melanoma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

基因資訊

human ... MLANA(2315)

相關類別

一般說明

MART-1 (also known as melan A) is a melanoma antigen recognized by T cells.1-2 MART-1 is a transmembrane protein present in melanocytes of normal skin, nevi, and most melanomas. MART-1 is a useful marker for identifying melanomas.

品質


IVD
IVD
IVD
RUO

聯結

MART-1 Positive Control Slides, Product No. 281S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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分析證明 (COA)

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Ravi Suchak et al.
The American Journal of dermatopathology, 36(5), 387-391 (2014-01-08)
To assess the usefulness of routine melan-A immunohistochemistry (IHC) for exclusion of microinvasion in lentigo maligna (LM). One hundred and twenty cases of LM from our archives were reviewed by 2 authors with S100 protein and melan-A IHC using a
Cynthia Kucher et al.
The American Journal of dermatopathology, 26(6), 452-457 (2004-12-25)
Desmoplastic melanoma (DMM) is an uncommon melanoma variant with a distinct morphology, including a prominent spindle cell component with fibrosis, as well as a distinct immunohistochemical profile. Histologically, the spindle cell component of DMM can be confused with sclerotic/desmoplastic nevi
P G Coulie et al.
The Journal of experimental medicine, 180(1), 35-42 (1994-07-01)
It has been reported previously that antitumor cytolytic T lymphocyte (CTL) clones can be isolated from blood lymphocytes of HLA-A2 melanoma patients, after stimulation in vitro with autologous tumor cells, and that some of these CTL clones lyse most HLA-A2
Y Kawakami et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(9), 3515-3519 (1994-04-26)
By cDNA expression cloning we have isolated a gene encoding a shared human melanoma antigen recognized by HLA-A2 restricted autologous and allogenic tumor-infiltrating lymphocytes (TILs) from patients with metastatic melanoma. By using both transient and stable expression systems, transfection of
Klaus Helm et al.
Journal of cutaneous pathology, 35(10), 931-934 (2008-05-23)
Distinguishing lentigo maligna from solar lentigo, and pigmented actinic keratosis can sometimes be problematic. Melan-A is an immunohistochemical marker which that can be helpful in decorating the melanocytes of pigmented lesions. A recent report has suggested that Melan-A may spuriously
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