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246R-1

Sigma-Aldrich

E-cadherin (EP700Y) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP700Y, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (246R-14)
vial of 0.5 mL concentrate (246R-15)
bottle of 1.0 mL predilute (246R-17)
vial of 1.0 mL concentrate (246R-16)
bottle of 7.0 mL predilute (246R-18)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

同型

IgG

控制

breast

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

membranous

一般說明

E-cadherin is a transmembrane protein that is involved in cell adhesion through the formationof adherens junctions between cells. It is expressed in cells of epithelial lineage. Anti-E-cadherin stains positively in the glandular epithelium as well as carcinomas of the gastrointestinaltract and breast. E-cadherin immunohistochemistry may also aid in the differentiation ofbreast ductal carcinomas (with membranous stain) from lobular carcinomas (with loss of themembranous stain).

品質


IVD

IVD

IVD

RUO

聯結

E-cadherin Positive Control Slides, Product No. 246S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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A C Han et al.
Cancer, 87(2), 83-86 (1999-05-05)
Cadherins are a family of cell-cell adhesion proteins. The homotypic binding of cadherins is critical for cell sorting and tissue formation during organogenesis. Different cadherin subtypes show lineage specific tissue expression, which has been exploited to differentiate histologically similar tumors
Amer Wahed et al.
Annals of diagnostic pathology, 6(6), 349-351 (2002-12-13)
Pleomorphic lobular carcinoma is a recently described entity separated from classical lobular carcinoma by cytologic pleomorphism. It can have an aggressive clinical course with a higher frequency of recurrence. Histologic differentiation with ductal carcinoma may be difficult, but it is
G Acs et al.
American journal of clinical pathology, 115(1), 85-98 (2001-02-24)
We studied the pattern of E-cadherin expression in 183 invasive carcinomas (100 ductal, 42 lobular, 41 with mixed ductal and lobular features) and 198 in situ carcinomas (131 ductal, 53 lobular, 14 in situ with ductal and lobular features) by
A Simsir et al.
Diagnostic cytopathology, 20(3), 125-130 (1999-03-23)
The distinction between reactive mesothelial cells (RMC), malignant mesothelioma (MM), and metastatic adenocarcinoma (ACA) in pleural effusions may be impossible based on morphology alone. E-cadherin, N-cadherin, and calretinin are newly described immunocytochemical markers which can potentially be utilized for facilitating
M P Leers et al.
Histopathology, 32(3), 209-216 (1998-05-06)
To assess the diagnostic accuracy of combinations of antibodies in the differential diagnosis of metastatic carcinomas and mesotheliomas in pleural lesions. The specificity and sensitivity of the commercially available antibodies Ber-EP4, MOC-31, CEA, B72.3, CD15, E-cadherin and calretinin were evaluated

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