22640

奎宁 半硫酸盐 一水合物

BioReagent, suitable for fluorescence, 99.0-101.0%

• 同義詞: Quinine sulfate (2:1) (salt) dihydrate
• 經驗公式（希爾表示法）: C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
• CAS號碼: 207671-44-1
• 分子量：: 391.47
• Beilstein: 6113937
• MDL號碼: MFCD00150790
• 分類程式碼代碼: 12352210
• PubChem物質ID: 329752330
• NACRES: NA.32

屬性

• 產品線: BioReagent
• 化驗: 99.0-101.0%
• mp: ~225 °C (dec.) (lit.)
• 螢光: λ_ex 347 nm; λ_em 448 nm in 0.5 M sulfuric acid
• 適合性: suitable for fluorescence
• 抗生素活性譜: parasites
• 作用方式: enzyme | inhibits
• SMILES 字串: O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
• InChI: 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
• InChI 密鑰: ZHNFLHYOFXQIOW-LPYZJUEESA-N

描述

一般說明

Quinine hemisulfate salt monohydrate is a naturally occurring well known fluorescent standard material. Quinine hemisulfate salt monohydrate or QSM has a fluorescence lifetime between 1.0 to 3.0 ns.

應用

Quinine hemisulfate salt monohydrate is used for indirect photometric detection of polyamines in biological samples. It is suitable for studying metabolism of bio crystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

生化／生理作用

钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂；最初从南美树木的金鸡纳科中分离出来的生物碱。

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves