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14699

Sigma-Aldrich

2-Deoxy-D-ribonic acid lithium salt

≥95.0% (TLC)

同義詞:

2-Deoxy-D-erythro-pentonic acid lithium salt

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About This Item

經驗公式(希爾表示法):
C5H10O5 · xLi+
CAS號碼:
分子量::
150.13 (free acid basis)
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

化驗

≥95.0% (TLC)

光學活性

[α]/D 12.0±2.0°, 24 hr, c = 1 in 1 M HCl

儲存溫度

2-8°C

SMILES 字串

OC[C@@H](O)[C@@H](O)CC(O)=O

InChI

1S/C5H10O5/c6-2-4(8)3(7)1-5(9)10/h3-4,6-8H,1-2H2,(H,9,10)/t3-,4+/m0/s1

InChI 密鑰

VBUWJOHKCBQXNU-IUYQGCFVSA-N

生化/生理作用

2-Deoxyribonic acid is the acid form of deoxyribonate, intercovertible with 2-Deoxy-ribonolactone, produced as part of bistranded lesions by DNA damaging agents, by ionizing radiation, organometallic oxidants, and is a metastable intermediate in DNA damage mediated by copper phenanthroline nucleases, and is also formed under anaerobic conditions in the presence of the radiosensitizing agent tirapazamine. It has been found in normal human biofluids.

其他說明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Cleavage of the intermediate hydroperoxides in the oxidation of D-glucose and D-fructose with oxygen.
Vuorinen, T.
Carbohydrate Research, 141, 319-322 (1985)
M Davies et al.
Acta endocrinologica, 104(2), 210-215 (1983-10-01)
Serum vitamin D metabolites, the renal tubular maximum reabsorptive rate for phosphate (TMP/GFR) nephrogenic cyclic AMP (NcAMPI, and CaE (urinary calcium excretion per litre of glomerular filtrate) were measured in 14 adults with familial hypocalciuric hypercalcaemia (FHH). The findings were
Kelly M Kroeger et al.
Biochemistry, 42(8), 2449-2455 (2003-02-26)
2-Deoxyribonolactone (3) is produced in DNA as a result of reaction with a variety of DNA damaging agents. The lesion undergoes beta-elimination to form a second metastable electrophilic product (4). In this study, DNA containing 2-deoxyribonolactone (3) and its beta-elimination
Formation of carboxylic acids during degradation of mono- saccharides.
Novotny, O., et al.
Czech Journal of Food Sciences, 26, 117-131 (2008)
Isolation of 2-deoxy-D-erythro-pentonic acid from an alkali-labile site in gamma-irradiated DNA.
M Dizdaroglu et al.
International journal of radiation biology and related studies in physics, chemistry, and medicine, 32(5), 481-483 (1977-11-01)

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