推薦產品
生物源
human plasma
化驗
≥90% (GE)
形狀
lyophilized solid
分子量
Mr ~28300
溶解度
H2O: 1 mg/mL, clear, colorless
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
基因資訊
human ... APOA1(335)
尋找類似的產品？ 前往 產品比較指南
一般說明
Apolipoprotein A-I (apoA-I) is the chief protein component of high density lipoproteins (HDL) and a major determinant of HDL structure, composition, and stability. It is an exchangeable apolipoprotein and plays pivotal role in the metabolism of cholesterol.
應用
Apolipoprotein A-I (apoA-I) was used for protecting the heart against vascular disease, it also protects other vascular beds and organs. It was protective against atherosclerosis through its ability to intervene in reverse cholesterol transport.
生化／生理作用
High-density lipoproteins are antiatherogenic and cardioprotective by facilitating reverse cholesterol transport (RCT). Some strategies for elevating apolipoprotein A-I levels are studied as therapies for atherosclerosis.
準備報告
lyophilized from 0.01 M ammonium hydrogen carbonate
其他說明
A principal protein component of high-density lipoproteins. Protein - lipid interactions
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
客戶也查看了
Weiling Wang et al.
Journal of lipid research, 51(9), 2560-2570 (2010-05-26)
The relationship between high-density lipoprotein and pulmonary function is unclear. To determine mechanistic relationships we investigated the effects of genetic deletion of apolipoprotein A-I (apoA-I) on plasma lipids, paraoxonase (PON1), pro-inflammatory HDL (p-HDL), vasodilatation, airway hyperresponsiveness and pulmonary oxidative stress
Jens O Lagerstedt et al.
Biochimica et biophysica acta, 1821(3), 448-455 (2012-01-17)
Apolipoprotein A-I (apoA-I) is the major protein component of high density lipoproteins (HDL) and plays a central role in cholesterol metabolism. The lipid-free/lipid-poor form of apoA-I is the preferred substrate for the ATP-binding cassette transporter A1 (ABCA1). The interaction of
R.B. Gennis et al.
Annual Review of Biophysics and Biophysical Chemistry, 6, 195-195 (1977)
Scott M Gordon et al.
Current opinion in endocrinology, diabetes, and obesity, 19(2), 109-114 (2012-01-27)
To review recently published advances in the development of apolipoprotein A-I (apoA-I) mimetic peptides as a potential treatment for cardiovascular diseases. Various apoA-I mimetic peptides are currently in development and these display potent cardioprotective features that can rival or even
Ryan J Henderson et al.
Lipids in health and disease, 8, 27-27 (2009-07-25)
Haptoglobin is a plasma protein that scavenges haemoglobin during haemolysis. Phospholipid Transfer Protein (PLTP) transfers lipids from Low Density Lipoproteins (LDL) to High Density Lipoproteins (HDL). PLTP is involved in the pathogenesis of atherosclerosis which causes coronary artery disease, the
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務