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Merck
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S2252

Sigma-Aldrich

亚硝酸钠

ReagentPlus®, ≥99.0%

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About This Item

線性公式:
NaNO2
CAS號碼:
分子量::
69.00
EC號碼:
MDL號碼:
分類程式碼代碼:
12352302
PubChem物質ID:
NACRES:
NA.21

品質等級

產品線

ReagentPlus®

化驗

≥99.0%

形狀

powder or crystals

自燃溫度

914 °F

pH值

9 (20 °C, 100 g/L)

mp

271 °C (lit.)

SMILES 字串

[Na+].[O-]N=O

InChI

1S/HNO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1

InChI 密鑰

LPXPTNMVRIOKMN-UHFFFAOYSA-M

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一般說明

亚硝酸钠是一种具有还原性和氧化性的空气敏感和吸湿性固体。它是合成有机化学中常用的试剂和催化剂。它被酸(甚至弱酸)分解,形成棕色的氮氧化物混合物(NOx)。

應用

亚硝酸钠可作为试剂用于:      
  • 在将胺转化为重氮化合物的过程中,重氮化合物被用作许多染料的关键前体,如重氮染料。      
  • Nef 反应和 Abidi 转化。      
  • 在 TFA 和有氧条件下的 C-C 键裂解反应。      
  • 在 K2S2O8 环境下烯烃的氧化羰化反应。

在有机合成中也可用作硝化剂。
它用于直接碳氢硝化、同位硝化和过渡金属催化的交叉偶联硝化。在有氧、无溶剂条件下,NaNO2 也被用作醇催化氧化的助催化剂。

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Ox. Sol. 3

儲存類別代碼

5.1B - Oxidizing hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Raquel Morais de Paiva Daibert et al.
PloS one, 15(11), e0241861-e0241861 (2020-11-07)
Macrophages are classified upon activation as classical activated M1 and M2 anti-inflammatory regulatory populations. This macrophage polarization is well characterized in humans and mice, but M1/M2 profile in cattle has been far less explored. Bos primigenius taurus (taurine) and Bos
Anne C Rios et al.
Cancer cell, 35(4), 618-632 (2019-04-02)
Breast tumors are inherently heterogeneous, but the evolving cellular organization through neoplastic progression is poorly understood. Here we report a rapid, large-scale single-cell resolution 3D imaging protocol based on a one-step clearing agent that allows visualization of normal tissue architecture
Rustem F Dautov et al.
Nitric oxide : biology and chemistry, 40, 36-44 (2014-05-27)
Previous studies in non-human blood vessels and in platelets have demonstrated that under hypoxic conditions release of NO from nitrite (NO2(-)) is potentiated by deoxyhaemoglobin. In the current study, we characterized hypoxic potentiation of NO2(-) effects in human vasculature and
Edward H Oldfield et al.
Journal of neurosurgery, 119(3), 634-641 (2013-05-28)
Intravenous sodium nitrite has been shown to prevent and reverse cerebral vasospasm in a primate model of subarachnoid hemorrhage (SAH). The present Phase IIA dose-escalation study of sodium nitrite was conducted to determine the compound's safety in humans with aneurysmal
Paul J Shami et al.
Journal of medicinal chemistry, 49(14), 4356-4366 (2006-07-11)
The literature provides evidence that metabolic nitric oxide (NO) release mediates the cytotoxic activities (against human leukemia and prostate cancer xenografts in mice) of JS-K, a compound of structure R(2)N-N(O)=NO-Ar for which R(2)N is 4-(ethoxycarbonyl)piperazin-1-yl and Ar is 2,4-dinitrophenyl. Here

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