RDD039

咪唑

for molecular biology, ≥99% (titration), free-flowing, Redi-Dri^™

• 同義詞: 1,3-二氮杂-2,4-环戊二烯, 甘恶啉
• 經驗公式（希爾表示法）: C₃H₄N₂
• CAS號碼: 288-32-4
• 分子量：: 68.08
• Beilstein: 103853
• MDL號碼: MFCD00005183
• 分類程式碼代碼: 12352200
• NACRES: NA.21

屬性

• 等級: for molecular biology
• 品質等級: 100
• 蒸汽壓力: <1 mmHg ( 20 °C)
• 產品線: Redi-Dri^™
• 化驗: ≥99% (titration)
• 形狀: crystalline powder
• 品質: free-flowing
• pH值: 6.2-7.8 (25 °C)
• pKa (25 °C): 6.95
• bp: 256 °C (lit.)
• mp: 88-91 °C (lit.)
• 應用: diagnostic assay manufacturing
• 異物活動: DNase, RNase and protease, none detected
• SMILES 字串: c1c[nH]cn1
• InChI: 1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)
• InChI 密鑰: RAXXELZNTBOGNW-UHFFFAOYSA-N

描述

一般說明

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar.

應用

Imidazole has been used

• in the lysis, wash, and elution buffer for the purification of histidine tagged proteins
• in gradient for the purification of histidine tagged proteins using nickel affinity chromatography
• as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells

特别适用于 pH 6.2-7.8 范围内的缓冲液

生化／生理作用

Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).

特點和優勢

• Qualified for molecular biology applications, DNase, Rnase, and protease free
• Redi-Dri^™ packaging controls moisture, eliminating clumps
• Crystalline powder remains free-flowing and much easier to use
• Safer to handle and weigh out for routine use in lab
• Less waste, loss of drying, while maintaining high quality

其他說明

For additional information on our range of Biochemicals, please complete this form.

法律資訊

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

安全資訊

• 象形圖: GHS08,GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H314,H360D
• 防範說明: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 293.0 °F - closed cup
• 閃點（°C）: 145 °C - closed cup